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硫氧还蛋白过氧化物酶2,Anti-PRDX2/Peroxiredoxin-SO3,一抗 价格优惠 上海现货
点击次数:274发布时间:2012/7/16 19:16:12
更新日期:2013/4/11 12:03:28
所 在 地:其它
产品型号:
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详细内容
硫氧还蛋白过氧化物酶2Anti-PRDX2/Peroxiredoxin-SO3MSP 23;MSP23;natural killer-enhancing factor A;NKEF A;NKEFA;PAG;PAGA;PAGB;
360TIYO.COM-上海田源公司
性能参数:
中文名称:硫氧还蛋白过氧化物酶2
英文名称:Anti-PRDX2/Peroxiredoxin-SO3
别名:MSP 23;MSP23;natural killer-enhancing factor A;NKEF A;NKEFA;PAG;PAGA;PAGB;
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.硫氧还蛋白过氧化物酶2的质量标准:
■其它名称: | MSP 23;MSP23;natural killer-enhancing factor A;NKEF A;NKEFA;PAG;PAGA;PAGB; |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | 细胞生物免疫学信号转导细胞凋亡 |
■蛋白分子: | predicted molecular weight: 22kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from hu PRDX2/Peroxiredoxin-SO3 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
■产品应用: | WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user. |
■保存条件: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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2、非质量报告提及的指标投诉
硫氧还蛋白过氧化物酶2Anti-PRDX2/Peroxiredoxin-SO3的相关产品目录:
(1mg/1ml硫氧还蛋白过氧化物酶2Anti-PRDX2/Peroxiredoxin-SO3,MSP 23;MSP23;natural killer-enhancing factor A;NKEF A;NKEFA;PAG;PAGA;PAGB;的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
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