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泛素蛋白连接酶2N抗体,Anti-Ube2N/UBC13,一抗 价格优惠 上海现货
点击次数:150发布时间:2012/7/16 19:17:14
更新日期:2013/4/11 12:02:49
所 在 地:其它
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详细内容
泛素蛋白连接酶2N抗体Anti-Ube2N/UBC13UBC 13; UBC13; UbCH ben; Ube 2N; Ube2n; UBE2N_HUMAN; ubiquitin carrier protein N; Ubiquiti
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性能参数:
中文名称:泛素蛋白连接酶2N抗体
英文名称:Anti-Ube2N/UBC13
别名:UBC 13; UBC13; UbCH ben; Ube 2N; Ube2n; UBE2N_HUMAN; ubiquitin carrier protein N; Ubiquiti
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). UBC13, also known as UBE2N or BLU, is a 152 amino acid member of the E2 ubiquitin-conjugating enzyme family. Existing as a heterodimer with Mms2 (also known as UBE2V2), UBC13 catalyzes the ATP-dependent synthesis of non-canonical polyubiquitin chains, a process that does not lead to proteasomal degradation. Additionally, UBC13 mediates the transcription of several target genes and is thought to play a role in cell cycle progression, cellular differentiation and DNA repair mechanisms that ensure cell survival after DNA damage.Subcellular Location : Nucleus. Cytoplasm.泛素蛋白连接酶2N抗体的质量标准:
■其它名称: | UBC 13; UBC13; UbCH ben; Ube 2N; Ube2n; UBE2N_HUMAN; ubiquitin carrier protein N; Ubiquiti |
■交叉反应: | hu, mo, rat, Rb, cow, chk, dog, hrs |
■产品类型: | 一抗 |
■应用领域: | 肿瘤细胞生物免疫学信号转导表观遗传学 |
■蛋白分子: | predicted molecular weight: 18kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Ube2N/UBC13 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
■产品应用: | WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:50-200(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user. |
■保存条件: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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泛素蛋白连接酶2N抗体Anti-Ube2N/UBC13的相关产品目录:
(1mg/1ml泛素蛋白连接酶2N抗体Anti-Ube2N/UBC13,UBC 13; UBC13; UbCH ben; Ube 2N; Ube2n; UBE2N_HUMAN; ubiquitin carrier protein N; Ubiquiti的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
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