产品展示
上皮钙粘附分子结合蛋白E7,Anti-CBLL1/Ecadherin binding protein E7,一抗 价格优惠 上海现货
点击次数:173发布时间:2012/7/16 19:17:45
更新日期:2013/4/11 11:59:52
所 在 地:其它
产品型号:
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详细内容
上皮钙粘附分子结合蛋白E7Anti-CBLL1/Ecadherin binding protein E7c-Cbl-like protein 1;CasBrM (murine) ecotropic retroviral transforming sequencelike 1;
360TIYO.COM-上海田源公司
性能参数:
中文名称:上皮钙粘附分子结合蛋白E7
英文名称:Anti-CBLL1/Ecadherin binding protein E7
别名:c-Cbl-like protein 1;CasBrM (murine) ecotropic retroviral transforming sequencelike 1;
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:CBLL1, also known as HAKAI (meaning "destruction’ in Japanese), or RNF188 (RING finger protein 188), is a 491 amino acid protein that contains one C2H2-type zinc finger and one RING-type zinc finger. CBLL1 is believed to function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. More specifically, upon activation of c-Src, CBLL1 interacts with and ubiquitinates tyrosine-phosphorylated E-cadherin, thereby targeting the E-cadherin complex for endocytosis and disrupting epithelial cell-cell contacts. Via its role as an E-cadherin regulator, CBLL1 participates in cell adhesion and may also be involved in the regulation of epithelial-mesenchymal transitions.上皮钙粘附分子结合蛋白E7的质量标准:
■其它名称: | c-Cbl-like protein 1;CasBrM (murine) ecotropic retroviral transforming sequencelike 1; |
■交叉反应: | Hu, mo, rat, chicken, dog |
■产品类型: | 一抗 |
■应用领域: | 细胞生物免疫学 |
■蛋白分子: | predicted molecular weight: 60kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from Hu CBLL1/Ecadherin binding protein E7 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
■产品应用: | WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:50-200(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user. |
■保存条件: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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上皮钙粘附分子结合蛋白E7Anti-CBLL1/Ecadherin binding protein E7的相关产品目录:
(1mg/1ml上皮钙粘附分子结合蛋白E7Anti-CBLL1/Ecadherin binding protein E7,c-Cbl-like protein 1;CasBrM (murine) ecotropic retroviral transforming sequencelike 1;的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
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