无毛发蛋白抗体Anti-HairlessHR; ALUNC; AU; HAIR_HUMAN; Hairless protein; Host range; HSA277165; Protein hairless.
360TIYO.COM-上海田源公司

性能参数：

中文名称：无毛发蛋白抗体
英文名称：Anti-Hairless
别名：HR; ALUNC; AU; HAIR_HUMAN; Hairless protein; Host range; HSA277165; Protein hairless.
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Hairless is a 1,189 amino acid protein which is expressed as two isoforms produced by alternative splicing. The two isoforms are expressed in a variety of tissues in varying concentrations. Isoform 1 is more abundant than isoform 2 ａnd is expressed at low levels in kidneys ａnd testis, while isoform 2 is expressed abundantly in skin. Both isoforms are also present together in many tissues ａnd are expressed strongly in small intestine ａnd brain ａnd weakly in trachea. HR is thought to be a transcription factor involved in hair growth. Hair growth occurs in three phases known as anagen, catagen ａnd telogen, which are phases where growth, regression ａnd rest, respectively, are taking place. By unknown mechanisms, HR is thought to regulate one of the hair growth phases ａnd to work with vitamin D receptor （VDR） to regulate hair follicle cycling. Defects in HR may cause two serious ailments, known as alopecia universalis congenita （ALUNC） ａnd atrichia with papular lesions （APL）, which is also referred to as congenital atrichia. Both are autosomally recessive impairments. ALUNC is a rare condition in which hair follicles are produced without hair, while APL is a serious disease in which papillary lesions may cover the body ａnd little to no hair is grown.Subcellular Location : Nucleus.Tissue Specificity : Strongest expression of isoforms 1 ａnd 2 is seen in the small intestine, weaker expression in brain ａnd colon, ａnd trace expression is found in liver, pancreas, spleen, thymus, stomach, salivary gland, appendix ａnd trachea. Isoform 1 is always the most abundant. Isoform 1 is exclusively expressed at low levels in kidney ａnd testis. Isoform 2 is exclusively expressed at high levels in the skin.Similarity : Contains 1 JmjC domain.

无毛发蛋白抗体的质量标准：

■其它名称：	HR; ALUNC; AU; HAIR_HUMAN; Hairless protein; Host range; HSA277165; Protein hairless.
■交叉反应：	hu, mo, rat, dog, shp, hrs, pig, cow, Rb
■产品类型：	一抗
■应用领域:	染色质和核信号 转录调节因子 表观遗传学
■蛋白分子：	predicted molecular weight: 60kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human Hairless
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
■产品应用：	WB=1:100-500ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500IF=1:50-200（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
■保存条件：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
4、田源将联系客户并提供质量投诉处理结果。

友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

无毛发蛋白抗体Anti-Hairless的相关产品目录：







（1mg/1ml无毛发蛋白抗体Anti-Hairless，HR; ALUNC; AU; HAIR_HUMAN; Hairless protein; Host range; HSA277165; Protein hairless.的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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