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突触蛋白6抗体,Anti-SynaptotagminVI,一抗 价格优惠 上海现货
点击次数:205发布时间:2012/7/16 20:04:17
更新日期:2013/4/11 11:53:14
所 在 地:其它
产品型号:
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详细内容
突触蛋白6抗体Anti-SynaptotagminVISynaptotagmin 6; Synaptotagmin6; SynaptotagminVI; Syt 6; Syt-6; Syt VI; Syt6; SytVI.
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性能参数:
中文名称:突触蛋白6抗体
英文名称:Anti-SynaptotagminVI
别名:Synaptotagmin 6; Synaptotagmin6; SynaptotagminVI; Syt 6; Syt-6; Syt VI; Syt6; SytVI.
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Synaptotagmins (Syts) are a large gene family of synaptic vesicle integral membrane proteins. Syt functions as regulators of both exocytosis/endocytosis and is involved in neurotransmitter secretion from smallsecretory vesicles. 13 isoforms of Syt have been identified(SytI-XIII).SynaptotagminVI is localized to the endoplasmic reticulum and/or Golgi like perinuclear compartment. It may be important for trafficking and calcium signaling as it is specially expressed in nonneuronal tissues. Also SytVI is present in the acrosomal region of mammalian spermatozoa. The cytosolic domain of SytVI can abrogate exocytosis by competing with the endogenous protein for essential interactions with the fusion machinery involved in a acrosomal exocytosis.Subcellular Location : Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Isoform 1: Membrane; Single-pass membrane protein. Note=Localized predominantly to endoplasmic reticulum (ER) and/or Golgi-like perinuclear compartment. Isoform 2: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein.Similarity : Belongs to the synaptotagmin family.Contains 2 C2 domains.Subunit : Homodimer (isoform 1). Isoform 1 forms heterodimers with SytIII, SytV and SytX. Interacts with STX1A, STX1B and STX2; the interaction is Ca(2+)-dependent. Isoform 2 is not able to form homodimer and heterodimers.突触蛋白6抗体的质量标准:
■其它名称: | Synaptotagmin 6; Synaptotagmin6; SynaptotagminVI; Syt 6; Syt-6; Syt VI; Syt6; SytVI. |
■交叉反应: | hu, mo, rat, hrs, cow, pig, Rb |
■产品类型: | 一抗 |
■应用领域: | 免疫学 神经生物学 信号转导 |
■蛋白分子: | predicted molecular weight: 56kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Synaptotagmin VI (385-430aa) |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■产品应用: | WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user. |
■保存条件: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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突触蛋白6抗体Anti-SynaptotagminVI的相关产品目录:
(1mg/1ml突触蛋白6抗体Anti-SynaptotagminVI,Synaptotagmin 6; Synaptotagmin6; SynaptotagminVI; Syt 6; Syt-6; Syt VI; Syt6; SytVI.的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
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