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磷酸化G蛋白通路抑制蛋白1抗体,Anti-phospho-GPS1/CSN1(Ser474),一抗磷酸化抗体 价格优惠 上海现货
点击次数:191发布时间:2012/7/17 22:17:59
更新日期:2013/5/6 13:07:14
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详细内容
磷酸化G蛋白通路抑制蛋白1抗体Anti-phospho-GPS1/CSN1(Ser474)CSN1 (phospho S474); phospho-GPS1(S474);p-GPS1(Ser474); Arabidopsis Fus6/Cop 11 homolog; A
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性能参数:
中文名称:磷酸化G蛋白通路抑制蛋白1抗体
英文名称:Anti-phospho-GPS1/CSN1(Ser474)
别名:CSN1 (phospho S474); phospho-GPS1(S474);p-GPS1(Ser474); Arabidopsis Fus6/Cop 11 homolog; A
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Suppresses G-protein-and mitogen-activated protein kinase-mediated signal transduction.Subcellular Location : Cytoplasm. Nucleus.Tissue Specificity : Widely expressed.磷酸化G蛋白通路抑制蛋白1抗体的质量标准:
■其它名称: | CSN1 (phospho S474); phospho-GPS1(S474);p-GPS1(Ser474); Arabidopsis Fus6/Cop 11 homolog; A |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | 细胞生物 免疫学 神经生物学 信号转导 激酶和磷酸酶 |
■蛋白分子: | predicted molecular weight: 60kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human GPS1 around the phosphorylation site of Ser474 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
■产品应用: | WB=1:100-500ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500IF=1:50-200(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user. |
■保存条件: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化G蛋白通路抑制蛋白1抗体Anti-phospho-GPS1/CSN1(Ser474)的相关产品目录:
(1mg/1ml磷酸化G蛋白通路抑制蛋白1抗体Anti-phospho-GPS1/CSN1(Ser474),CSN1 (phospho S474); phospho-GPS1(S474);p-GPS1(Ser474); Arabidopsis Fus6/Cop 11 homolog; A的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
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