细胞死亡调解子抗体Anti-Bim/BCL2L11Bcl-2 interacting mediator of cell death; Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacti
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性能参数：

中文名称：细胞死亡调解子抗体
英文名称：Anti-Bim/BCL2L11
别名：Bcl-2 interacting mediator of cell death; Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacti
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Background: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers ａnd act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 （BH3）. It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X（L）, ａnd MCL1, ａnd to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor （NGF）, as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal ａnd lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq].Subcellular Location : Mitochondrion ａnd Endomembrane system. Associated with intracytoplasmic membranes.Tissue Specificity : Isoform BimEL, isoform BimL ａnd isoform BimS are the predominant isoforms ａnd are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine ａnd colon, ａnd in lower levels in spleen, prostate, testis, heart, liver ａnd kidney.Bim是Bcl-2家族BH3-only亚家族的成员,是一种重要的凋亡调节蛋白，具有助凋亡活性作用。Bim广泛表达于正常细胞,对防御自身免疫、维持造血细胞稳态有重要意义,并具有肿瘤抑制因子活性.Bim的生理作用与它调节细胞凋亡的功能有关。

细胞死亡调解子抗体的质量标准：

■其它名称：	Bcl-2 interacting mediator of cell death; Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacti
■交叉反应：	hu, mo, rat, cow, hrs, shp, pig, dog
■产品类型：	一抗
■应用领域:	/细胞生物/神经生物学/细胞凋亡/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 22kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from the middle of human Bim
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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1、向我们的客户服务部反应投诉原因及订单信息。
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部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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细胞死亡调解子抗体Anti-Bim/BCL2L11的相关产品目录：







1mg/1ml 细胞死亡调解子抗体 Anti-Bim/BCL2L11 Bcl-2 interacting mediator of cell death; Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacti的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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