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半胱胺酸蛋白酶蛋白-12抗体,Anti-Caspase-12,一抗 价格优惠 上海现货
点击次数:107发布时间:2012/7/22 23:13:45
更新日期:2013/5/6 9:48:05
所 在 地:其它
产品型号:
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详细内容
半胱胺酸蛋白酶蛋白-12抗体Anti-Caspase-12UNQ9415; Apoptosis related cysteine protease; CASP 12; casp12; CASP12P1; Caspase 12 pseudo
360TIYO.COM-上海田源公司
性能参数:
中文名称:半胱胺酸蛋白酶蛋白-12抗体
英文名称:Anti-Caspase-12
别名:UNQ9415; Apoptosis related cysteine protease; CASP 12; casp12; CASP12P1; Caspase 12 pseudo
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Three distinct signaling pathways lead to apoptosis. The death receptor and mitochondrion pathways are the two mains, which involve respectively caspase-8 and caspase-9. The endoplasmic reticulum stress is the third apoptotic pathway and involves caspase-12. Localized to the ER but not to cytoplasm or mitochondria, caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including g-secretase presenilin and b-amyloid precursor protein (APP). Caspase-12 mediates ER stress-induced apoptosis as well as cytotoxicity induced by amyloid-b. Caspase-12 is ubiquitously expressed in mouse tissues.Tissue Specificity : Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis.Similarity : Belongs to the peptidase C14A family.Contains 1 CARD domain.ASPASE-12是caspase家族成员,是存在于内质网上的促凋亡因子,内质网应激早期可通过GRP(glucose-regulated protein,GRP)的表达增多来保护细胞;CASPASE-12是内质网细胞关键介导因子,caspase-12还是caspase-1的抑制剂。半胱胺酸蛋白酶蛋白-12抗体的质量标准:
■其它名称: | UNQ9415; Apoptosis related cysteine protease; CASP 12; casp12; CASP12P1; Caspase 12 pseudo |
■交叉反应: | hu |
■产品类型: | 一抗 |
■应用领域: | /细胞凋亡 |
■蛋白分子: | predicted molecular weight: 38kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from the middle of human Caspase-12 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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由于化学产品的特殊性,恕不接受以下投诉:
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2、非质量报告提及的指标投诉
半胱胺酸蛋白酶蛋白-12抗体Anti-Caspase-12的相关产品目录:
1mg/1ml 半胱胺酸蛋白酶蛋白-12抗体 Anti-Caspase-12 UNQ9415; Apoptosis related cysteine protease; CASP 12; casp12; CASP12P1; Caspase 12 pseudo的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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