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磷酸化中心粒蛋白Nudel抗体,Anti-phospho-NDEL1(Ser231),一抗磷酸化抗体 价格优惠 上海现货
点击次数:151发布时间:2012/7/23 11:44:34
更新日期:2013/4/11 10:58:45
所 在 地:其它
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详细内容
磷酸化中心粒蛋白Nudel抗体Anti-phospho-NDEL1(Ser231)NDEL1(phospho S231); Nudel(phospho S231); EOPA; MITAP 1; MITAP1; Mitosin associated protei
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性能参数:
中文名称:磷酸化中心粒蛋白Nudel抗体
英文名称:Anti-phospho-NDEL1(Ser231)
别名:NDEL1(phospho S231); Nudel(phospho S231); EOPA; MITAP 1; MITAP1; Mitosin associated protei
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Nudel is important for normal cortical development. It is invovled in microtubule organization, nuclear translocation, and neuronal positioning in concert with various other factors (including Lis1, Pafah1b1, Pahfah1b2, dynein, dynorphin A and cdk5). Western blot analysis of mouse tissues shows abundant expression of Nudel in brain and testis, and much lower expression in heart, liver, kidney, and skeletal muscle. In fractionated rat brain, Nudel and Lis1 are both found in fractions enriched for postsynaptic density proteins. Immunostaining of embryonic day 18 mouse brain sections revealed staining of migrating neurons and thalamocortical axons of the intermediate zone of the developing cerebral cortex, as well as several other developing brain regions. The deduced protein contains 345 amino acids and has a calculated molecular mass of 38.4 kDa. It has a coiled coil motif (residues 19 to 201), followed by several potential phosphorylation sites for casein kinase II, protein kinase C or CDK5. Nudel shares about 50% identity with mouse and human NUDE proteins.Subcellular Location : Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle.Tissue Specificity : Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.Similarity : Belongs to the nudE family.Subunit : Interacts with YWHAE.中心粒蛋白Nudel是动物细胞中,中心体微管组织的主要细胞器,是细胞质动力蛋白调节因子在中心体组装及徽管组织中发挥重要作用。磷酸化中心粒蛋白Nudel抗体的质量标准:
■其它名称: | NDEL1(phospho S231); Nudel(phospho S231); EOPA; MITAP 1; MITAP1; Mitosin associated protei |
■交叉反应: | hu, mo, rat, cow, hrs, chk, dog, pig, Rb |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /免疫学/染色质和核信号/神经生物学/信号转导/转录调节因子 |
■蛋白分子: | predicted molecular weight: 38kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human NDEL1 around the phosphorylation site of Ser231 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化中心粒蛋白Nudel抗体Anti-phospho-NDEL1(Ser231)的相关产品目录:
1mg/1ml 磷酸化中心粒蛋白Nudel抗体 Anti-phospho-NDEL1(Ser231) NDEL1(phospho S231); Nudel(phospho S231); EOPA; MITAP 1; MITAP1; Mitosin associated protei的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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