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Ⅰ型补体受体抗体(C3b/C4b受体抗体),Anti-CR1/CD35,一抗 价格优惠 上海现货
点击次数:199发布时间:2012/7/23 22:16:12
更新日期:2013/5/3 17:02:24
所 在 地:其它
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详细内容
Ⅰ型补体受体抗体(C3b/C4b受体抗体)Anti-CR1/CD35Complement receptor type 1; CR1; C3BR; C4BR; CD35; KN; C3-binding protein; CD35 antigen; c
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性能参数:
中文名称:Ⅰ型补体受体抗体(C3b/C4b受体抗体)
英文名称:Anti-CR1/CD35
别名:Complement receptor type 1; CR1; C3BR; C4BR; CD35; KN; C3-binding protein; CD35 antigen; c
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized.Subcellular Location : Membrane; Single-pass type I membrane protein.Tissue Specificity : Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells.Similarity : Belongs to the receptors of complement activation (RCA) family.Contains 30 Sushi (CCP/SCR) domains.Subunit : Monomer. CD35广泛分布于红细胞、粒细胞、单核细胞、肥大细胞、滤泡树突状细胞、肾小球足突细胞、B细胞及部分CD4+T细胞表面.CD35抗原又称为CR1或者C3b/C4b R,是一种分子量160-250kDa的C3b/C4b补体结合跨膜蛋白,主要用于滤泡树突状细胞标记和滤泡树突状细胞瘤的诊断。Ⅰ型补体受体抗体(C3b/C4b受体抗体)的质量标准:
■其它名称: | Complement receptor type 1; CR1; C3BR; C4BR; CD35; KN; C3-binding protein; CD35 antigen; c |
■交叉反应: | hu |
■产品类型: | 一抗 |
■应用领域: | /免疫学/细胞膜受体/淋巴细胞/t-淋巴细胞/b-淋巴细胞 |
■蛋白分子: | predicted molecular weight: 274kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human CR1 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//Flow-Cyt=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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Ⅰ型补体受体抗体(C3b/C4b受体抗体)Anti-CR1/CD35的相关产品目录:
1mg/1ml Ⅰ型补体受体抗体(C3b/C4b受体抗体) Anti-CR1/CD35 Complement receptor type 1; CR1; C3BR; C4BR; CD35; KN; C3-binding protein; CD35 antigen; c的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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