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磷酸化c-fos抗体,Anti-Phospho-c-Fos(Thr232),一抗磷酸化抗体 价格优惠 上海现货
点击次数:136发布时间:2012/7/25 0:01:13
更新日期:2013/5/3 16:17:06
所 在 地:其它
产品型号:
优质供应
详细内容
磷酸化c-fos抗体Anti-Phospho-c-Fos(Thr232)Cellular oncogene fos; FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ O
360TIYO.COM-上海田源公司
性能参数:
中文名称:磷酸化c-fos抗体
英文名称:Anti-Phospho-c-Fos(Thr232)
别名:Cellular oncogene fos; FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ O
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. Nuclear phosphoprotein which forms a tight but non- covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, c-fos and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. Subunit: Heterodimer with JUN. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB. Belongs to the bZIP family. Fos subfamily. Subcellular Location: Nucleus.c-fos的作用主要用于各种类型的恶性肿瘤如食管癌、鼻咽癌、乳腺癌、结肠癌以及脑病的研究。 c-fos原癌基因及其蛋白产物不仅参与细胞的正常生长、分化过程,而且也参与细胞内信息传递过程和细胞的能量代谢过程,对细胞的增生、分化、转化都有调节作用、在生命活动中起着极为基础而重要的作用。磷酸化c-fos抗体的质量标准:
■其它名称: | Cellular oncogene fos; FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ O |
■交叉反应: | mo |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /转录调节因子 |
■蛋白分子: | predicted molecular weight: 60kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from mouse c-Fos around the phosphorylation site of Thr232 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化c-fos抗体Anti-Phospho-c-Fos(Thr232)的相关产品目录:
1mg/1ml 磷酸化c-fos抗体 Anti-Phospho-c-Fos(Thr232) Cellular oncogene fos; FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ O的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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