细胞角蛋白20抗体Anti-CK20Cytokeratin 20; CK 20; CK20; Cytokeratin20; K20; Keratin 20; Keratin type I cytoskeletal 2
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性能参数：

中文名称：细胞角蛋白20抗体
英文名称：Anti-CK20
别名：Cytokeratin 20; CK 20; CK20; Cytokeratin20; K20; Keratin 20; Keratin type I cytoskeletal 2
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Cytokeratin 20 is a type I keratin which is primarily expressed in gastric ａnd intestinal epithelium, urothelium, ａnd Merkel-cells. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells ａnd are subdivided into cytokeratins ａnd hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Their genes are clustered in a region of chromosome 17q12-q21. Cytokeratin 20 is a major cellular protein of mature enterocytes ａnd goblet cells ａnd is specifically expressed in the gastric ａnd intestinal mucosa. It is also expressed in adenocarcinomas of the colon, stomach, pancreas ａnd the bile system ａnd is present in mucinous ovarian tumors, transitional-cell ａnd Merkel-cell carcinomas. Notably, the squamous cell carcinomas ａnd adenocarcinomas of the breast, lung, ａnd endometrium, non-mucinous tumors of the ovary, ａnd small cell carcinomas lack cytokeratin 20.Subcellular Location : Cytoplasm.Tissue Specificity : Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa ａnd in the taste buds of lingual mucosa.Similarity : Belongs to the intermediate filament family.Subunit : Heterotetramer of two type I ａnd two type II keratins. Associates with KRT8.结构蛋白（Structural Proteins） CK-20细胞角蛋白-20主要用于肿瘤方面的研究，近年来大多用于消化系统恶性肿瘤的鉴别，主要在胞浆。

细胞角蛋白20抗体的质量标准：

■其它名称：	Cytokeratin 20; CK 20; CK20; Cytokeratin20; K20; Keratin 20; Keratin type I cytoskeletal 2
■交叉反应：	hu, rat, mo
■产品类型：	一抗
■应用领域:	/肿瘤/免疫学
■蛋白分子：	predicted molecular weight: 46kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human CK20 C-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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细胞角蛋白20抗体Anti-CK20的相关产品目录：







1mg/1ml 细胞角蛋白20抗体 Anti-CK20 Cytokeratin 20; CK 20; CK20; Cytokeratin20; K20; Keratin 20; Keratin type I cytoskeletal 2的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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