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细胞角蛋白18抗体Anti-CK18CK-18; Cell proliferation inducing gene 46 protein; Cell proliferation inducing protein 46
360TIYO.COM-上海田源公司
性能参数:
中文名称:细胞角蛋白18抗体
英文名称:Anti-CK18
别名:CK-18; Cell proliferation inducing gene 46 protein; Cell proliferation inducing protein 46
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18.Tissue Specificity : Expressed in endoderm, intestinal epithelial cells and in most extraembryonic tissues.Similarity : Belongs to the intermediate filament family.Subunit : Heterotetramer of two type I and two type II keratins. KRT18 associates with KRT8. Interacts with PNN, HCV core protein and mutated CFTR. Interacts with YWHAE, YWHAH and YWHAZ only when phosphorylated. Interacts with the thrombin-antithrombin complex. Interacts with DNAJB6, TCHP and TRADD (By similarity).结构蛋白(Structural Proteins)常用于肿瘤细胞的分化、增殖及转移方面的研究。细胞角蛋白18抗体的质量标准:
■其它名称: | CK-18; Cell proliferation inducing gene 46 protein; Cell proliferation inducing protein 46 |
■交叉反应: | hu, mo, rat, Rb, cow, hrs, dog, pig |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/信号转导/细胞类型标志物 |
■蛋白分子: | predicted molecular weight: 48kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human CK18 (53-96aa) |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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细胞角蛋白18抗体Anti-CK18的相关产品目录:
1mg/1ml 细胞角蛋白18抗体 Anti-CK18 CK-18; Cell proliferation inducing gene 46 protein; Cell proliferation inducing protein 46的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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