细胞角蛋白7抗体（人）Anti-CK7（human）Cytokeratin 7; CK 7; K7; Keratin 7; Keratin,type II cytoskeletal 7; KRT7; SCL.
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性能参数：

中文名称：细胞角蛋白7抗体（人）
英文名称：Anti-CK7（human）
别名：Cytokeratin 7; CK 7; K7; Keratin 7; Keratin,type II cytoskeletal 7; KRT7; SCL.
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Cytokeratins are a subfamily of intermediate filament proteins ａnd are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa ａnd 68 kDa ａnd isoelectric pH between 4.9 – 7.8. The individual human cytokeratins are designated 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology ａnd flow cytometric assays. Cytokeratin 7 is a 54kD intermediate filament protein found in a variety of glandularepithelia. Cytokeratin 7 has been found in columnar ａnd glandular epithelium of the lung, cervix, breast, bile ducts ａnd larger collecting ducts of the kidney. It is present in the transitional epitheliumof bladder as well as ovarian ａnd lungepithelia, ａnd occasionally staining of blood vessel cell walls, particularly endothelial cells, may be observed. However, Cytokeratin 7 is not expressed by epithelial cells of the gastrointestinal tract, colon or prostate. Keratin 7 is often co expressed with keratin 19.结构蛋白（Structural Proteins） CK-7是一种 54KDa 的中间丝蛋白，存在于大多数正常组织的腺上皮和移行上皮细胞中。 该抗体与多种良/恶性上皮性肿瘤反应。腺癌中的卵巢、乳腺、肺的腺癌呈阳性反应，而胃肠道的腺癌阴性。移行细胞肿瘤、前列腺癌也呈阳性反应。通常认为 CK7是腺癌和移行上皮细胞癌的比较特异性的标志。

细胞角蛋白7抗体（人）的质量标准：

■其它名称：	Cytokeratin 7; CK 7; K7; Keratin 7; Keratin,type II cytoskeletal 7; KRT7; SCL.
■交叉反应：	hu
■产品类型：	一抗
■应用领域:	/肿瘤/信号转导/细胞类型标志物
■蛋白分子：	predicted molecular weight: 54kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from the middle of human CK7
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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细胞角蛋白7抗体（人）Anti-CK7（human）的相关产品目录：







1mg/1ml 细胞角蛋白7抗体（人） Anti-CK7（human） Cytokeratin 7; CK 7; K7; Keratin 7; Keratin,type II cytoskeletal 7; KRT7; SCL.的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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