细胞角蛋白14抗体Anti-CK14/17/42/10Cytokeratin 14; CK 14; ck14; Cytokeratin14; Dowling Meara; ebs3; Epidermolysis bullosa sim
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性能参数：

中文名称：细胞角蛋白14抗体
英文名称：Anti-CK14/17/42/10
别名：Cytokeratin 14; CK 14; ck14; Cytokeratin14; Dowling Meara; ebs3; Epidermolysis bullosa sim
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Keratin 14 is a member of the keratin family, the most diverse group of intermediate filaments. It is usually found as a heterotetramer with two molecules of keratin 5, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. Keratin 14 has been studied as a prognostic marker in breast cancer.Subcellular Location : Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern.Tissue Specificity : Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.Similarity : Belongs to the intermediate filament family.Subunit : Heterotetramer of two type I ａnd two type II keratins. keratin-14 associates with keratin-5. Interacts with TRADD ａnd with keratin filaments. Associates with other type I keratins.CK14属于酸性角蛋白。在乳腺腺体和导管肌上皮细胞、唾液腺腺泡和导管的肌上皮细胞以及鳞状上皮的基底细胞中阳性表达。大多数鳞状细胞癌表达阳性，并且阳性表达的频率与其分化程度无明显关系。主要用于鳞状细胞癌的判断，尤其用于低分化鳞癌判断中。

细胞角蛋白14抗体的质量标准：

■其它名称：	Cytokeratin 14; CK 14; ck14; Cytokeratin14; Dowling Meara; ebs3; Epidermolysis bullosa sim
■交叉反应：	hu, mo, rat, cow, hrs, shp, dog, Rb
■产品类型：	一抗
■应用领域:	/肿瘤
■蛋白分子：	predicted molecular weight: 52kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human CK14 C-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

细胞角蛋白14抗体Anti-CK14/17/42/10的相关产品目录：







1mg/1ml 细胞角蛋白14抗体 Anti-CK14/17/42/10 Cytokeratin 14; CK 14; ck14; Cytokeratin14; Dowling Meara; ebs3; Epidermolysis bullosa sim的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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