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高分子量细胞角蛋白抗体,Anti-Cytokeratin 13/CK-HMW,一抗 价格优惠 上海现货
点击次数:157发布时间:2012/7/26 15:25:08
更新日期:2013/5/3 15:44:32
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详细内容
高分子量细胞角蛋白抗体Anti-Cytokeratin 13/CK-HMWHMW Cytokeratin; type I cytoskeletal 13; 47 kDa cytokeratin; CK-13; CK13; Cytokeratin 13;
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中文名称:高分子量细胞角蛋白抗体
英文名称:Anti-Cytokeratin 13/CK-HMW
别名:HMW Cytokeratin; type I cytoskeletal 13; 47 kDa cytokeratin; CK-13; CK13; Cytokeratin 13;
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue. There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1 (67), CK2 (65.5), CK3 (64), CK4 (59), CK5 (58), CK6 (56), CK7 (54), CK8 (52.5) and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10 (56.5), CK12 (56), CK13 (53), CK14 (50), CK16( 48), CK17 (46), CK18 (45), CK19(48) and CK20(46).Tissue Specificity : Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) . WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.Similarity : Belongs to the intermediate filament family.Subunit : Heterotetramer of two type I and two type II keratins. keratin-13 is generally associated with keratin-4.高分子量细胞角蛋白抗体的质量标准:
■其它名称: | HMW Cytokeratin; type I cytoskeletal 13; 47 kDa cytokeratin; CK-13; CK13; Cytokeratin 13; |
■交叉反应: | hu, mo, rat, cow, hrs, dog |
■产品类型: | 一抗 |
■应用领域: | /肿瘤 |
■蛋白分子: | predicted molecular weight: 49kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human CK-HMW |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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高分子量细胞角蛋白抗体Anti-Cytokeratin 13/CK-HMW的相关产品目录:
1mg/1ml 高分子量细胞角蛋白抗体 Anti-Cytokeratin 13/CK-HMW HMW Cytokeratin; type I cytoskeletal 13; 47 kDa cytokeratin; CK-13; CK13; Cytokeratin 13; 的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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