细胞角蛋白8抗体Anti-CK8Cytokeratin 8; CK8 （card2; Cardiac autoantigen 2 120kD; CK 8; ck8; Cyk 8; cyk8; Cytokerat
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性能参数：

中文名称：细胞角蛋白8抗体
英文名称：Anti-CK8
别名：Cytokeratin 8; CK8 （card2; Cardiac autoantigen 2 120kD; CK 8; ck8; Cyk 8; cyk8; Cytokerat
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Cytokeratin 8 belongs to the type B （basic） subfamily of high molecular weight keratins ａnd exists in combination with cytokeratin 18. Cytokeratin 8 is primarily found in the non squamous epithelia ａnd is present in majority of adenocarcinomas ａnd ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 ａnd 18.Cytokeratins are a subfamily of intermediate filament proteins ａnd are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa ａnd 68 kDa ａnd isoelectric pH between 4.9 – 7.8. The individual cytokeratin polypeptides are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology ａnd flow cytometric assays.结构蛋白（Structural Proteins） 上皮细胞胞质中的骨架蛋白除微丝（肌动蛋白）、微管蛋白外，主要是细胞角蛋白（cytokeratins，CK）。CK8也是上皮细胞的特征性标记物：CK8存在于某些正常腺上皮及其肿瘤，包括许多导管上皮和腺上皮，如结肠、胃、小肠、气管的上皮和尿路上皮。CK8主要用于腺癌和导管癌的诊断，鳞状细胞癌一般不表达CK8。

细胞角蛋白8抗体的质量标准：

■其它名称：	Cytokeratin 8; CK8 （card2; Cardiac autoantigen 2 120kD; CK 8; ck8; Cyk 8; cyk8; Cytokerat
■交叉反应：	hu, mo, rat, pig, dog, chk
■产品类型：	一抗
■应用领域:	/肿瘤/细胞生物/信号转导/细胞类型标志物
■蛋白分子：	predicted molecular weight: 42kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human CK8 N-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
4、田源将联系客户并提供质量投诉处理结果。

友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

细胞角蛋白8抗体Anti-CK8的相关产品目录：







1mg/1ml 细胞角蛋白8抗体 Anti-CK8 Cytokeratin 8; CK8 （card2; Cardiac autoantigen 2 120kD; CK 8; ck8; Cyk 8; cyk8; Cytokerat的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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