产品展示
磷酸化细胞角蛋白17抗体,Anti-Phospho-CK17 (Ser44),一抗磷酸化抗体 价格优惠 上海现货
点击次数:174发布时间:2012/7/26 15:27:02
更新日期:2013/5/3 15:44:03
所 在 地:其它
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详细内容
磷酸化细胞角蛋白17抗体Anti-Phospho-CK17 (Ser44)39.1; CK 17; Cytokeratin17; K17; Keratin 17 antibody Keratin type I cytoskeletal 17; Kerat
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性能参数:
中文名称:磷酸化细胞角蛋白17抗体
英文名称:Anti-Phospho-CK17 (Ser44)
别名:39.1; CK 17; Cytokeratin17; K17; Keratin 17 antibody Keratin type I cytoskeletal 17; Kerat
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial 'stem cells'. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation (By similarity). [SUBUNIT] Heterodimer of a type I and a type II keratin. KRT17 associates with KRT6 isomers. Interacts with TRADD and SFN. Belongs to the intermediate filament family.结构蛋白(Structural Proteins)常用于肿瘤细胞的分化、增殖及转移方面的研究。磷酸化细胞角蛋白17抗体的质量标准:
■其它名称: | 39.1; CK 17; Cytokeratin17; K17; Keratin 17 antibody Keratin type I cytoskeletal 17; Kerat |
■交叉反应: | hu, rat, mo |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/免疫学/转录调节因子 |
■蛋白分子: | predicted molecular weight: 48kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human CK 17 around the phosphorylation site of Ser44 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化细胞角蛋白17抗体Anti-Phospho-CK17 (Ser44)的相关产品目录:
1mg/1ml 磷酸化细胞角蛋白17抗体 Anti-Phospho-CK17 (Ser44) 39.1; CK 17; Cytokeratin17; K17; Keratin 17 antibody Keratin type I cytoskeletal 17; Kerat的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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