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田源抗体,磷酸化信号淋巴细胞活化分子CD150抗体,Anti-phospho-SLAMF1(Tyr281),一抗磷酸化抗体 上海 价格
点击次数:170发布时间:2012/7/30 11:34:52
更新日期:2013/4/11 10:44:04
所 在 地:其它
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详细内容
磷酸化信号淋巴细胞活化分子CD150抗体Anti-phospho-SLAMF1(Tyr281)SLAMF1(phospho Y281); CD150 antigen; Cdw150; Estm51; Ipo 3; Ipo3; MGC151472; MGC151476; Si
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性能参数:
中文名称:磷酸化信号淋巴细胞活化分子CD150抗体
英文名称:Anti-phospho-SLAMF1(Tyr281)
别名:SLAMF1(phospho Y281); CD150 antigen; Cdw150; Estm51; Ipo 3; Ipo3; MGC151472; MGC151476; Si
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:SLAM, a novel glycoprotein of 37kDa, designated SLAM (Signaling Lymphocyte Activation Molecule) or CDw150, belongs to the immunoglobulin gene superfamily and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form of SLAM and the soluble and cytoplasmic isoforms of SLAM, and the expression levels of membrane bound SLAM on B cells are rapidly regulated after activation in vitro. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells.CD150(SLAM)为70kD的表面糖蛋白属于免疫球蛋白基因超家族。SLAM有直接诱导CD4阳性T细胞克隆与活化前T细胞的作用。CD150抗原还可以增强抗原特异性增生与通过T细胞携带的CD4抗原产生细胞因子,特别是对干扰素-γ具有极强的上调节作用。SLAM与自身配体具有极高亲和性,由SLAM同源亲和细胞间的相互作用能够刺激T淋巴细胞产生自身因子。CD150抗原还是风疹病毒细胞受体并且通过白介素10下调节。磷酸化信号淋巴细胞活化分子CD150抗体的质量标准:
■其它名称: | SLAMF1(phospho Y281); CD150 antigen; Cdw150; Estm51; Ipo 3; Ipo3; MGC151472; MGC151476; Si |
■交叉反应: | hu, rat, mo |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /免疫学/信号转导/t-淋巴细胞/b-淋巴细胞 |
■蛋白分子: | predicted molecular weight: 70kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human SLAMF1 around the phosphorylation site of Tyr281 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化信号淋巴细胞活化分子CD150抗体Anti-phospho-SLAMF1(Tyr281)的相关产品目录:
1mg/1ml 磷酸化信号淋巴细胞活化分子CD150抗体 Anti-phospho-SLAMF1(Tyr281) SLAMF1(phospho Y281); CD150 antigen; Cdw150; Estm51; Ipo 3; Ipo3; MGC151472; MGC151476; Si的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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