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田源抗体,周期素D3抗体,Anti-Cyclin D3,一抗 上海 价格
点击次数:127发布时间:2012/7/30 11:43:17
更新日期:2013/4/11 10:43:36
所 在 地:其它
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详细内容
周期素D3抗体Anti-Cyclin D3CCND3; CyclinD3; D3 type cyclin; G1 S specific cyclin D3.
360TIYO.COM-上海田源公司
性能参数:
中文名称:周期素D3抗体
英文名称:Anti-Cyclin D3
别名:CCND3; CyclinD3; D3 type cyclin; G1 S specific cyclin D3.
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclinsexhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.细胞周期素是周期素依赖激酶的调节因子,不同的细胞周期素控制着细胞周期中不同的特定阶段。 周期素D3与周期素D1和D2一样,为细胞周期中G1期进入S期的一个重要调控因子,通过激活CdK4或CdK6等作用,促进DNA合成,加速细胞增殖,主要用于B细胞淋巴瘤、乳腺癌、头颈部鳞癌、食道癌、肝癌和肺癌等恶性肿瘤的研究。周期素D3抗体的质量标准:
■其它名称: | CCND3; CyclinD3; D3 type cyclin; G1 S specific cyclin D3. |
■交叉反应: | hu, mo, rat, pig, cow, dog, Rb |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/细胞生物/细胞周期蛋白 |
■蛋白分子: | predicted molecular weight: 32kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Cyclin D3 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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周期素D3抗体Anti-Cyclin D3的相关产品目录:
1mg/1ml 周期素D3抗体 Anti-Cyclin D3 CCND3; CyclinD3; D3 type cyclin; G1 S specific cyclin D3. 的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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