周期素E2抗体Anti-Cyclin E2CCN E2; CCNE 2; CCNE2; CCNE2 protein; CYC E2; CYCE 2; CYCE2; CyclinE2; G1/S-specific cycli
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性能参数：

中文名称：周期素E2抗体
英文名称：Anti-Cyclin E2
别名：CCN E2; CCNE 2; CCNE2; CCNE2 protein; CYC E2; CYCE 2; CYCE2; CyclinE2; G1/S-specific cycli
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 （Kip1） ａnd p21 （Cip1）. Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. Unlike Cyclin E1, which is expressed in great majority of proliferating normal ａnd neoplastically transformed cells, Cyclin E2 levels are low to undetectable in non transformed cells ａnd increase significantly in neoplasm derived cells.Subcellular Location : Nucleus.Tissue Specificity : According to PubMed:9858585, highest levels of expression in adult testis, thymus ａnd brain. Lower levels in placenta, spleen ａnd colon. Consistently elevated levels in tumor-derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, ａnd kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus ａnd brain. In a lesser extent in small intestine ａnd colon.Similarity : Belongs to the cyclin family. Cyclin E subfamily.Subunit : "Interacts with the CDK2 （in vivo） ａnd CDK3 （in vitro） protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex.

周期素E2抗体的质量标准：

■其它名称：	CCN E2; CCNE 2; CCNE2; CCNE2 protein; CYC E2; CYCE 2; CYCE2; CyclinE2; G1/S-specific cycli
■交叉反应：	hu, mo, rat, cow, hrs, pig, Rb
■产品类型：	一抗标签抗体
■应用领域:	/肿瘤/细胞生物/免疫学/染色质和核信号/信号转导/细胞周期蛋白
■蛋白分子：	predicted molecular weight: 44kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human Cyclin E2
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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周期素E2抗体Anti-Cyclin E2的相关产品目录：







1mg/1ml 周期素E2抗体 Anti-Cyclin E2 CCN E2; CCNE 2; CCNE2; CCNE2 protein; CYC E2; CYCE 2; CYCE2; CyclinE2; G1/S-specific cycli的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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