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田源抗体,地西泮结合抑制因子抗体,Anti-PBR/DBI/Diazepam binding inhibitor,一抗 上海 价格
点击次数:210发布时间:2012/7/31 14:10:10
更新日期:2013/4/11 10:39:31
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详细内容
地西泮结合抑制因子抗体Anti-PBR/DBI/Diazepam binding inhibitorBPBS; BZRP; DBI; IBP; Isoquinoline carboxamide-binding protein; MBR; mDRC; Mitochondrial b
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性能参数:
中文名称:地西泮结合抑制因子抗体
英文名称:Anti-PBR/DBI/Diazepam binding inhibitor
别名:BPBS; BZRP; DBI; IBP; Isoquinoline carboxamide-binding protein; MBR; mDRC; Mitochondrial b
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:PBR (Peripheral type Benzodiazepine Receptor) is a ubiquitous protein (18 kDa) found in most steroidogenic tissues. It is located primarily in the outer mitochondrial membrane of steroid producing tissues and is found in association with a 34 kDa voltage dependent anion channel protein (VDAC). PBR interacts with some benzodiazepines and has different affinities than its endogenous counterpart. PBR appears to be a key factor in the transport of cholesterol from the outer to the inner mitochondrial membrane to permit the initiation of steroid hormone synthesis. It is thought to be part of the mitochondrial permeability transition pore (PT) and to be involved in apoptosis. It is speculated that patients with congenital lipoid adrenal hyperplasia, who cannot make any steroids, might have a genetic lesion in BZRP. A short form, PBRS is also expressed in the same tissues, but at a level about ten times that of PBR.地西泮结合抑制因子;DBI能拮抗安定物质:diazepam与脑突触膜相结合 ,故称之为安定结合抑制蛋白(DBI),地西泮结合抑制因子(diazepam binding inhibitor,DBI)具有抑制由葡萄糖诱导的胰岛素分泌、促进胆固醇跨线粒体膜转运和调节脂肪酸合成与代谢等多种生理功能。地西泮结合抑制因子抗体的质量标准:
■其它名称: | BPBS; BZRP; DBI; IBP; Isoquinoline carboxamide-binding protein; MBR; mDRC; Mitochondrial b |
■交叉反应: | hu, mo, rat, pig, dog |
■产品类型: | 一抗 |
■应用领域: | /细胞生物/免疫学/神经生物学/转录调节因子/糖尿病 |
■蛋白分子: | predicted molecular weight: 18kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human PBR |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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地西泮结合抑制因子抗体Anti-PBR/DBI/Diazepam binding inhibitor的相关产品目录:
1mg/1ml 地西泮结合抑制因子抗体 Anti-PBR/DBI/Diazepam binding inhibitor BPBS; BZRP; DBI; IBP; Isoquinoline carboxamide-binding protein; MBR; mDRC; Mitochondrial b的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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