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田源抗体,胱抑素C/半胱氨酸蛋白酶抑制剂C抗体,Anti-Cystatin C/CST3,一抗 上海 价格
点击次数:176发布时间:2012/7/31 14:11:39
更新日期:2013/4/11 10:38:58
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胱抑素C/半胱氨酸蛋白酶抑制剂C抗体Anti-Cystatin C/CST3Cystatin 3; Cystatin-3; CST 3;CST3; CST-3; Cystatin C; AD 8; AD8; Amyloid angiopathy and
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中文名称:胱抑素C/半胱氨酸蛋白酶抑制剂C抗体
英文名称:Anti-Cystatin C/CST3
别名:Cystatin 3; Cystatin-3; CST 3;CST3; CST-3; Cystatin C; AD 8; AD8; Amyloid angiopathy and
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq].胱抑素C( cystatin c)又称胱抑素C.是一种半胱氨酸蛋白酶抑制剂,也被称为γ-微量蛋白及γ-后球蛋白,广泛存在于各种组织的有核细胞和体液中,是一种低分子量、碱性非糖化蛋白质,分子量为13.3KD,由122个氨基酸残基组成,可由机体所有有核细胞产生,产生率恒定。循环中的胱抑素c仅经肾小球滤过而被清除,是一种反映肾小球滤过率变化的内源性标志物,并在近曲小管重吸收,但重吸收后被代谢分解,不返回血液,因此,其血中浓度由肾小球滤过决定,而不依赖任何外来因素,如性别、年龄、饮食的影响,是一种反映肾小球滤过率变化的理想同源性标志物。胱抑素C/半胱氨酸蛋白酶抑制剂C抗体的质量标准:
■其它名称: | Cystatin 3; Cystatin-3; CST 3;CST3; CST-3; Cystatin C; AD 8; AD8; Amyloid angiopathy and |
■交叉反应: | mo, rat, hu |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/心血管/细胞生物/免疫学/发育生物学 |
■蛋白分子: | predicted molecular weight: 13kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from mouse Cystatin 3 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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胱抑素C/半胱氨酸蛋白酶抑制剂C抗体Anti-Cystatin C/CST3的相关产品目录:
1mg/1ml 胱抑素C/半胱氨酸蛋白酶抑制剂C抗体 Anti-Cystatin C/CST3 Cystatin 3; Cystatin-3; CST 3;CST3; CST-3; Cystatin C; AD 8; AD8; Amyloid angiopathy and的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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