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多巴胺受体D1抗体Anti-DRD1D(1A) dopamine receptor; D1A dopamine receptor; Dopamine D1Receptors; D1DR; DADR; Dopamine
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性能参数:
中文名称:多巴胺受体D1抗体
英文名称:Anti-DRD1
别名:D(1A) dopamine receptor; D1A dopamine receptor; Dopamine D1Receptors; D1DR; DADR; Dopamine
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2 mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. Dopamine receptor D1 has been reported mostly in various regions of the brain. ESTs have been isolated from normal olfactory epithelium and cancerous genitourinary tract libraries.Subcellular Location : Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.Tissue Specificity : Detected in caudate, nucleus accumbens and in the olfactory tubercle.Similarity : Belongs to the G-protein coupled receptor 1 family.Subunit : Interacts with DNAJC14 via its C-terminus. Interacts with DRD1IP.多巴胺受体D1在运动协调方面起重要作用,该受体的缺失对黑质多巴胺能神经元的影响程度虽没临床帕金森病(PD)严重,但仍可加速多巴胺能神经元发生退行性改变.该蛋白目前主要用于神经退行性改变的研究。多巴胺受体D1抗体的质量标准:
■其它名称: | D(1A) dopamine receptor; D1A dopamine receptor; Dopamine D1Receptors; D1DR; DADR; Dopamine |
■交叉反应: | hu, rat, mo |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/免疫学/神经生物学 |
■蛋白分子: | predicted molecular weight: 50kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human DRD1 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//Flow-Cyt=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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多巴胺受体D1抗体Anti-DRD1的相关产品目录:
1mg/1ml 多巴胺受体D1抗体 Anti-DRD1 D(1A) dopamine receptor; D1A dopamine receptor; Dopamine D1Receptors; D1DR; DADR; Dopamine的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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