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田源抗体,表皮生长因子受体3抗体,Anti-ErbB-3/HER3,一抗 上海 价格
点击次数:164发布时间:2012/7/31 14:15:10
更新日期:2013/4/11 9:55:22
所 在 地:其它
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详细内容
表皮生长因子受体3抗体Anti-ErbB-3/HER3c erbB 3; c-erbB3; ERBB3; cerbB3; ERBB3 protein; cerbB; 3erbB3 S; Glial growth factor rec
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性能参数:
中文名称:表皮生长因子受体3抗体
英文名称:Anti-ErbB-3/HER3
别名:c erbB 3; c-erbB3; ERBB3; cerbB3; ERBB3 protein; cerbB; 3erbB3 S; Glial growth factor rec
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The ErbB3 gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized.表皮生长因子受体3抗体的质量标准:
■其它名称: | c erbB 3; c-erbB3; ERBB3; cerbB3; ERBB3 protein; cerbB; 3erbB3 S; Glial growth factor rec |
■交叉反应: | hu, rat, mo |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/免疫学/转录调节因子/激酶和磷酸酶/细胞膜受体 |
■蛋白分子: | predicted molecular weight: 147kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from the middle of human ErbB-3 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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表皮生长因子受体3抗体Anti-ErbB-3/HER3的相关产品目录:
1mg/1ml 表皮生长因子受体3抗体 Anti-ErbB-3/HER3 c erbB 3; c-erbB3; ERBB3; cerbB3; ERBB3 protein; cerbB; 3erbB3 S; Glial growth factor rec的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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