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田源抗体,细胞转录因子ELK1抗体,Anti-ELK1,一抗 上海 价格
点击次数:159发布时间:2012/7/31 14:16:38
更新日期:2013/4/11 9:54:52
所 在 地:其它
产品型号:
优质供应
详细内容
细胞转录因子ELK1抗体Anti-ELK1ELK 1; ELK1 member of ETS oncogene family; ELK1 protein; ELK2 member of ETS oncogene famil
360TIYO.COM-上海田源公司
性能参数:
中文名称:细胞转录因子ELK1抗体
英文名称:Anti-ELK1
别名:ELK 1; ELK1 member of ETS oncogene family; ELK1 protein; ELK2 member of ETS oncogene famil
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The transcription factor Elk1 is a component of the ternary complex that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors. Elk1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C terminus. Phosphorylation at these sites, particularly Ser383, is critical for transcriptional activation by Elk1. Elk1 appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk1 is a good substrate for MAP kinase, the kinetics of Elk1 phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block Elk1 activation in vivo. More recent studies have shown that Elk1 (Ser383) is also a target of the Stress Activated Kinase SAPK/JNK. Phosphorylation of Elk1 has also been implicated in synaptic plasticity in the adult hippocampus.转录调节因子(Transcriptin Regulators) 细胞转录因子ELK1是ETS致癌基因家族的一种。细胞转录因子ELK1抗体的质量标准:
■其它名称: | ELK 1; ELK1 member of ETS oncogene family; ELK1 protein; ELK2 member of ETS oncogene famil |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/免疫学/转录调节因子 |
■蛋白分子: | predicted molecular weight: 45kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human ELK1 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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细胞转录因子ELK1抗体Anti-ELK1的相关产品目录:
1mg/1ml 细胞转录因子ELK1抗体 Anti-ELK1 ELK 1; ELK1 member of ETS oncogene family; ELK1 protein; ELK2 member of ETS oncogene famil的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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