产品展示
田源抗体,表皮生长因子抗体(人),Anti-EGF(human),一抗 上海 价格
点击次数:158发布时间:2012/7/31 14:18:09
更新日期:2013/4/11 9:54:51
所 在 地:其它
产品型号:
优质供应
详细内容
表皮生长因子抗体(人)Anti-EGF(human)Beta urogastrone; Epidermal Growth Factor; Pro epidermal growth factor; URG; Urogastrone.
360TIYO.COM-上海田源公司
性能参数:
中文名称:表皮生长因子抗体(人)
英文名称:Anti-EGF(human)
别名:Beta urogastrone; Epidermal Growth Factor; Pro epidermal growth factor; URG; Urogastrone.
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Epidermal growth factor (EGF) has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells. The EGF precursor is believed to exist as a membrane bound molecule which is proteolytically cleaved to generate the 53 amino acid peptide hormone that stimulates cells to divide. EGF exerts its actions by binding to the EGFR, a 170 kDa protein.Epidermal growth factor (EGF) is a key growth factor regulating cell survival. Through its binding to cell surface receptors, EGF activates an extensive network of signal transduction pathways that include activation of the PI3K/AKT, RAS/ERK and JAK/STAT pathways. Because of its key role in driving the proliferation of cells, EGFR is a target of several anti-cancer drugs currently in development. 表皮生长因子是一种小肽,由53个氨基酸残基组成, 是类EGF大家族的一个成员,是一种多功能的生长因子,在体内体外都对多种组织细胞有强烈的促分裂作用。EGF同应答细胞表面的特异受体结合,一旦结合,便促进受体二聚化并使细胞质位点磷酸化。被激活的受体至少可与5种具有不同信号序列的蛋白结合,进行信号转导,在翻译水平上对蛋白质的合成起调节作用。此外EGF可提高细胞内DNA拓扑异构酶活性,也可促进一些与增殖有关的基因表达,如myc 、fos等。表皮生长因子抗体(人)的质量标准:
■其它名称: | Beta urogastrone; Epidermal Growth Factor; Pro epidermal growth factor; URG; Urogastrone. |
■交叉反应: | hu |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/细胞生物/免疫学/生长因子和激素 |
■蛋白分子: | predicted molecular weight: 5.8/133kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human EGF C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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表皮生长因子抗体(人)Anti-EGF(human)的相关产品目录:
1mg/1ml 表皮生长因子抗体(人) Anti-EGF(human) Beta urogastrone; Epidermal Growth Factor; Pro epidermal growth factor; URG; Urogastrone.的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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