细胞色素P450 3A4抗体Anti-CYP3A4Cytochrome p450 3A4; CP33; CP34; CYP3A; CYP3A3; CYP3A4; CYPIIIA4; Cytochrome P450 family 3
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性能参数：

中文名称：细胞色素P450 3A4抗体
英文名称：Anti-CYP3A4
别名：Cytochrome p450 3A4; CP33; CP34; CYP3A; CYP3A3; CYP3A4; CYPIIIA4; Cytochrome P450 family 3
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Cytochromes P450 are a group of heme thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH dependent electron transport pathway. It performs a variety of oxidation reactions （e.g. caffeine 8 oxidation, omeprazole sulphoxidation, midazolam 1 hydroxylation ａnd midazolam 4 hydroxylation） of structurally unrelated compounds, including steroids, fatty acids, ａnd xenobiotics. The enzyme also hydroxylates etoposide.Subcellular Location : Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.Tissue Specificity : Expressed in prostate ａnd liver. According to some authors, it is not expressed in brain （PubMed:19094056）. According to others, weak levels of expression are measured in some brain locations （PubMed:19359404 ａnd PubMed:18545703）. Also expressed in epithelium of the small intestine ａnd large intestine, bile duct, nasal mucosa, kidney, adrenal cortex, epithelium of the gastric mucosa with intestinal metaplasia, gallbladder, intercalated ducts of the pancreas, chief cells of the parathyroid ａnd the corpus luteum of the ovary （at protein level）.Similarity : Belongs to the cytochrome P450 family.细胞色素3A4（CYP3A4）是细胞色素P450 超家族成员, 主要存在于肝脏中和小肠中。它是人类药物代谢酶中的*重要的酶, CYP3A4与外源性致癌物、抗癌药物和内源性类固醇激素、维生素、脂肪酸的代谢转化密切相关。

细胞色素P450 3A4抗体的质量标准：

■其它名称：	Cytochrome p450 3A4; CP33; CP34; CYP3A; CYP3A3; CYP3A4; CYPIIIA4; Cytochrome P450 family 3
■交叉反应：	hu, mo, rat, pig, dog, Rb, cow, Gpig
■产品类型：	一抗
■应用领域:	/肿瘤/细胞生物/新陈代谢/线粒体
■蛋白分子：	predicted molecular weight: 55kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human CYP3A4 18-53aa
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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细胞色素P450 3A4抗体Anti-CYP3A4的相关产品目录：







1mg/1ml 细胞色素P450 3A4抗体 Anti-CYP3A4 Cytochrome p450 3A4; CP33; CP34; CYP3A; CYP3A3; CYP3A4; CYPIIIA4; Cytochrome P450 family 3的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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