整合素样金属蛋白酶与凝血酶9型抗体Anti-ADAMTS9A disintegrin ａnd metalloproteinase with thrombospondin motifs 9; ADAM TS 9; ADAM TS9; A d
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性能参数：

中文名称：整合素样金属蛋白酶与凝血酶9型抗体
英文名称：Anti-ADAMTS9
别名：A disintegrin ａnd metalloproteinase with thrombospondin motifs 9; ADAM TS 9; ADAM TS9; A d
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens ａnd von Willebrand factor as well as catabolism of aggrecan, versican ａnd brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis ａnd cell migration. ADAMTS9 is closest in homology to ADAMTS20, sharing 54% overall identity, ａnd like ADAMTS20 ADAMTS9 gas a GON like domain at the carboxyterminal end. The GON domain at the carboxyterminal end is similar to the GON1 protein in C. elegans, mutations of which lead to defective gonadal development. ADAMTS9 is expressed in ovary ａnd testis, but little is known about the role of ADAMTS9 in reproductive organs. ADAMTS9 is also expressed in the heart, placenta, lung, skeletal tissue, ａnd pancreas, so the protein must have wider functions than just gonadal development. ADAMTS9, like ADAMTS20, has a total of 15 thrombospondin like domains. The first TS domain begins shortly after the catalytic ａnd disintegrin domains. TS domains 2 to 6 follow a spacer domain, followed by linker domain 1, then TS domains 7 & 8, linker domain 2, ａnd then TS domains 9 to 15. In other ADAMTS proteins the TS motifs are thought to bind to the ECM. The ADAMTS proteins contain at least one prohormone convertase cleavage site, although it appears that one site is used preferentially, ａnd cleavage of the propeptide domain at this site generates active enzymes. For ADAMTS9, this site is the RRTKR sequence, ａnd the mature ADAMTS9 has an aminoterminal sequence of FLSYPR. The catalytic site of ADAMTS9 is most like ADAMTS1, 14 ａnd 15, with an HExxHVFNMxH sequence, perhaps giving these enzymes some shared specificity.细胞外基质蛋白

整合素样金属蛋白酶与凝血酶9型抗体的质量标准：

■其它名称：	A disintegrin ａnd metalloproteinase with thrombospondin motifs 9; ADAM TS 9; ADAM TS9; A d
■交叉反应：	hu, mo, rat
■产品类型：	一抗
■应用领域:	/肿瘤/细胞生物/免疫学/信号转导/细胞粘附分子/锌指蛋白
■蛋白分子：	predicted molecular weight: 217/183/121kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human ADAMTS9
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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整合素样金属蛋白酶与凝血酶9型抗体Anti-ADAMTS9的相关产品目录：







1mg/1ml 整合素样金属蛋白酶与凝血酶9型抗体 Anti-ADAMTS9 A disintegrin ａnd metalloproteinase with thrombospondin motifs 9; ADAM TS 9; ADAM TS9; A d的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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