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田源抗体,磷酸化叉头蛋白家族抗体,Anti-Phospho-FoxO1(Thr24)/FoxO3a(Thr32),一抗磷酸化抗体 上海 价格
点击次数:157发布时间:2012/8/1 11:41:34
更新日期:2013/4/11 9:21:49
所 在 地:其它
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详细内容
磷酸化叉头蛋白家族抗体Anti-Phospho-FoxO1(Thr24)/FoxO3a(Thr32)Forkhead box protein O1; Afxh; AI876417; FKHR; Fkhr1; Foxo1a; Forkhead; forkhead box prote
360TIYO.COM-上海田源公司
性能参数:
中文名称:磷酸化叉头蛋白家族抗体
英文名称:Anti-Phospho-FoxO1(Thr24)/FoxO3a(Thr32)
别名:Forkhead box protein O1; Afxh; AI876417; FKHR; Fkhr1; Foxo1a; Forkhead; forkhead box prote
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:FOXO1A (FKHR or ForkHead in Rhabdomyosarcoma) is a 70 kDa protein which is a member of a subfamily of the forkhead homeotic gene family of transcription factors. Recent studies have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C terminus of the FOXO1A protein. The specific function of the gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Chromosomal aberrations involving FOXO1A are a cause of rhabdomyosarcoma 2 (RMS2); also known as alveolar rhabdomyosarcoma.Subcellular Location : Cytoplasm, cytosol. Nucleus.Tissue Specificity : Ubiquitous.Similarity : Contains 1 fork-head DNA-binding domain.FoxO家族蛋白是一类转录因子,通过结合到下游基因启动子而激活一系列重要基因来调节细胞的重要生命过程。FoxO1(叉头蛋白家族1)是FOXO家族的重要一员,该蛋白主要调节细胞衰老、细胞周期、代谢及抗肿瘤的作用。FoxO1是诱导细胞自噬的关键蛋白,其抗癌作用与其诱导自噬功能密切相关。磷酸化叉头蛋白家族抗体的质量标准:
■其它名称: | Forkhead box protein O1; Afxh; AI876417; FKHR; Fkhr1; Foxo1a; Forkhead; forkhead box prote |
■交叉反应: | hu, mo, rat, cow, Rb, pig, chk, dog |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/免疫学/信号转导/细胞凋亡/转录调节因子/激酶和磷酸酶 |
■蛋白分子: | predicted molecular weight: 74kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human FOXO1 around the phosphorylation site of Thr24 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化叉头蛋白家族抗体Anti-Phospho-FoxO1(Thr24)/FoxO3a(Thr32)的相关产品目录:
1mg/1ml 磷酸化叉头蛋白家族抗体 Anti-Phospho-FoxO1(Thr24)/FoxO3a(Thr32) Forkhead box protein O1; Afxh; AI876417; FKHR; Fkhr1; Foxo1a; Forkhead; forkhead box prote的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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