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田源抗体,丝裂原活化蛋白激酶3抗体,Anti-ERK1/MAPK3,一抗 上海 价格
点击次数:116发布时间:2012/8/1 11:43:26
更新日期:2013/4/11 9:21:35
所 在 地:其它
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详细内容
丝裂原活化蛋白激酶3抗体Anti-ERK1/MAPK3ERK 1; ERK; ERK1; ERT 2; ERT2; Extracellular Signal Regulated Kinase 1; Extracellular sign
360TIYO.COM-上海田源公司
性能参数:
中文名称:丝裂原活化蛋白激酶3抗体
英文名称:Anti-ERK1/MAPK3
别名:ERK 1; ERK; ERK1; ERT 2; ERT2; Extracellular Signal Regulated Kinase 1; Extracellular sign
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1. Phosphorylates heat shock factor protein 4(HSF4) (By similarity). Highest levels within the nervous system, expressed in different tissues, mostly in intestine, placenta and lung. Increased expression during development. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. Contains 1 protein kinase domain.Subcellular Location : Cytoplasm. Nucleus. Note=Autophosphorylation at Thr-207 promotes nuclear localization.Similarity : Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. Contains 1 protein kinase domain.Subunit : Binds both upstream activators and downstream substrates in multimolecular complexes. Found in a complex with at least BRAF, HRAS1, MAP2K1/MEK1, MAPK3 and RGS14 (By similarity). Binds to HIV-1 Nef through its SH3 domain. This interaction inhibits its tyrosine-kinase activity. Interacts with ADAM15, ARRB2, CANX, DAPK1 (via death domain), HSF4, IER3, MAP2K1/MEK1, MORG1, NISCH, and SGK1. Interacts with PEA15 and MKNK2 (By similarity). MKNK2 isoform 1 binding prevents from dephosphorylation and inactivation (By similarity).丝裂原活化蛋白激酶3抗体的质量标准:
■其它名称: | ERK 1; ERK; ERK1; ERT 2; ERT2; Extracellular Signal Regulated Kinase 1; Extracellular sign |
■交叉反应: | hu, rat, mo |
■产品类型: | 一抗 |
■应用领域: | /细胞生物/免疫学/神经生物学/信号转导/细胞凋亡/激酶和磷酸酶 |
■蛋白分子: | predicted molecular weight: 44kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human MAPK1 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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丝裂原活化蛋白激酶3抗体Anti-ERK1/MAPK3的相关产品目录:
1mg/1ml 丝裂原活化蛋白激酶3抗体 Anti-ERK1/MAPK3 ERK 1; ERK; ERK1; ERT 2; ERT2; Extracellular Signal Regulated Kinase 1; Extracellular sign的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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