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田源抗体,内皮细胞受体蛋白酪氨酸激酶A抗体(肿瘤坏死因子α诱导蛋白4),Anti-EphA1/Ephrina1/Ephrin A1 Receptor,一抗 上海 价格
点击次数:218发布时间:2012/8/1 11:47:02
更新日期:2013/5/3 17:03:34
所 在 地:其它
产品型号:
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详细内容
内皮细胞受体蛋白酪氨酸激酶A抗体(肿瘤坏死因子α诱导蛋白4)Anti-EphA1/Ephrina1/Ephrin A1 ReceptorAlternative names for Eph receptor A1; Ephrin A1 Receptor; B61; ECKLG; EFL1; EPH; EPH rel
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性能参数:
中文名称:内皮细胞受体蛋白酪氨酸激酶A抗体(肿瘤坏死因子α诱导蛋白4)
英文名称:Anti-EphA1/Ephrina1/Ephrin A1 Receptor
别名:Alternative names for Eph receptor A1; Ephrin A1 Receptor; B61; ECKLG; EFL1; EPH; EPH rel
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The Eph family of receptors comprises the largest known family of receptor tyrosine kinases. Ligands of Eph family receptors are structurally related membrane-bound proteins that can be subdivided into two major subclasses, ephrin-A and ephrin-B. Expression of Eph receptors is tissue specific and appears to be tied to developmental events. Ligands in the ephrin-A subclass, including the prototype family member ephrin-A1 (B61), are membrane associated through glycosylphosphatidyl-inositol linkages, whereas ephrin-B subclass consists of ligands with transmembrane domains. The general role of the Eph family is in mediating repulsive cell-cell interaction.Subcellular Location : Cell membrane; Single-pass type I membrane protein.Tissue Specificity : Overexpressed in several carcinomas.Similarity : Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.Contains 1 Eph LBD (Eph ligand-binding) domain. Contains 2 fibronectin type-III domains. Contains 1 protein kinase domain. Contains 1 SAM (sterile alpha motif) domain.Subunit : Homodimer. Forms a signaling complex with LCK; PTK2B/PYK2 and PI3-kinase upon activation by EFNA1; regulates T-lymphocytes migration. Interacts (via SAM domain) with ILK (via ANK repeats); stimulated by EFNA1 but independent of the kinase activity of EPHA1. Interacts (kinase activity-dependent) with PTK2/FAK1.内皮细胞受体蛋白酪氨酸激酶A抗体(肿瘤坏死因子α诱导蛋白4)的质量标准:
■其它名称: | Alternative names for Eph receptor A1; Ephrin A1 Receptor; B61; ECKLG; EFL1; EPH; EPH rel |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/心血管/神经生物学/激酶和磷酸酶/细胞表面分子 |
■蛋白分子: | predicted molecular weight: 107kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Ephrin A1 R |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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内皮细胞受体蛋白酪氨酸激酶A抗体(肿瘤坏死因子α诱导蛋白4)Anti-EphA1/Ephrina1/Ephrin A1 Receptor的相关产品目录:
1mg/1ml 内皮细胞受体蛋白酪氨酸激酶A抗体(肿瘤坏死因子α诱导蛋白4) Anti-EphA1/Ephrina1/Ephrin A1 Receptor Alternative names for Eph receptor A1; Ephrin A1 Receptor; B61; ECKLG; EFL1; EPH; EPH rel的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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