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田源抗体,凝血因子13抗体(纤维蛋白稳定因子),Anti-factor XIII,一抗 上海 价格
点击次数:199发布时间:2012/8/1 11:48:48
更新日期:2013/3/22 10:48:16
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详细内容
凝血因子13抗体(纤维蛋白稳定因子)Anti-factor XIIIcoagulation factor XIII; F13A1; TGase; FXIIIA; F13A; Coagulation factor XIII A chain; Coa
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性能参数:
中文名称:凝血因子13抗体(纤维蛋白稳定因子)
英文名称:Anti-factor XIII
别名:coagulation factor XIII; F13A1; TGase; FXIIIA; F13A; Coagulation factor XIII A chain; Coa
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.凝血因子13抗体(纤维蛋白稳定因子)的质量标准:
■其它名称: | coagulation factor XIII; F13A1; TGase; FXIIIA; F13A; Coagulation factor XIII A chain; Coa |
■交叉反应: | hu, mo, rat, cow, dog, pig, Rb |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/细胞生物/免疫学/生长因子和激素 |
■蛋白分子: | predicted molecular weight: 79kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human factor XIII C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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凝血因子13抗体(纤维蛋白稳定因子)Anti-factor XIII的相关产品目录:
1mg/1ml 凝血因子13抗体(纤维蛋白稳定因子) Anti-factor XIII coagulation factor XIII; F13A1; TGase; FXIIIA; F13A; Coagulation factor XIII A chain; Coa的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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