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田源抗体,酪氨酸蛋白激酶受体B6抗体,Anti-EphB6,一抗 上海 价格
点击次数:116发布时间:2012/8/1 11:48:56
更新日期:2013/3/22 10:48:16
所 在 地:其它
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详细内容
酪氨酸蛋白激酶受体B6抗体Anti-EphB6EPH receptor B6; EphB6; EPHRIN RECEPTOR EphB6; Ephrin type B receptor 6 precursor; HEP; MG
360TIYO.COM-上海田源公司
性能参数:
中文名称:酪氨酸蛋白激酶受体B6抗体
英文名称:Anti-EphB6
别名:EPH receptor B6; EphB6; EPHRIN RECEPTOR EphB6; Ephrin type B receptor 6 precursor; HEP; MG
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands. [provided by RefSeq, Jul 2008].Subcellular Location : Membrane; Single-pass type I membrane protein. Isoform 3: Secreted.Tissue Specificity : Expressed in brain. Expressed in non invasive breast carcinoma cell lines (at protein level). Strong expression in brain and pancreas, and weak expression in other tissues, such as heart, placenta, lung, liver, skeletal muscle and kidney. Expressed in breast non invasive tumors but not in metastatic lesions. Isoform 3 is expressed in cell lines of glioblastomas, anaplastic astrocytomas, gliosarcomas and astrocytomas. Isoform 3 is not detected in normal tissues.Similarity : Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.Contains 1 Eph LBD (Eph ligand-binding) domain.Contains 2 fibronectin type-III domains.Subunit : Interacts with CBL and EPHB1. Interacts with FYN; this interaction takes place in a ligand-independent manner.生长因子和激素( Growth Factor and Hormones) 有学者认为:EPHB6受体型酪氨酸蛋白激酶与多种肿瘤的发生和转移负相关,EPHB6作为一种重要的生物学标记,还有许多未知的蛋白功能。酪氨酸蛋白激酶受体B6抗体的质量标准:
■其它名称: | EPH receptor B6; EphB6; EPHRIN RECEPTOR EphB6; Ephrin type B receptor 6 precursor; HEP; MG |
■交叉反应: | hu, mo, rat, pig, hrs, dog |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/免疫学/生长因子和激素/细胞表面分子 |
■蛋白分子: | predicted molecular weight: 111kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human EphB6 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//Flow-Cyt=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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酪氨酸蛋白激酶受体B6抗体Anti-EphB6的相关产品目录:
1mg/1ml 酪氨酸蛋白激酶受体B6抗体 Anti-EphB6 EPH receptor B6; EphB6; EPHRIN RECEPTOR EphB6; Ephrin type B receptor 6 precursor; HEP; MG的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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