核苷酸内焦磷酸酶/磷酸二酯酶1抗体Anti-ENPP1ENPP1; ENPP 1; ENPP-1; PC1; PC-1; ectonucleotide pyrophosphatase/phosphodiesterase 1; Plas
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性能参数：

中文名称：核苷酸内焦磷酸酶/磷酸二酯酶1抗体
英文名称：Anti-ENPP1
别名：ENPP1; ENPP 1; ENPP-1; PC1; PC-1; ectonucleotide pyrophosphatase/phosphodiesterase 1; Plas
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：ENPP1 has a broad specificity ａnd cleaves a variety of substrates, including phosphodiester bonds of nucleotides ａnd nucleotide sugars ａnd pyrophosphate bonds of nucleotides ａnd nucleotide sugars. It can hydrolyze nucleoside 5＇ triphosphates such as ATP, GTP, CTP, TTP ａnd UTP to their corresponding monophosphates with release of pyrophosphate. It can also hydrolyze diadenosine polyphosphates ａnd 3＇,5＇-cAMP to AMP. It may play a role in the regulation of pyrophosphate production, the regulation of the availability of nucleotide sugars in the endoplasmic reticulum ａnd Golgi, ａnd the regulation of purinergic signaling.The subtilisin-like Prohormone Convertase （PC） family is a group of cellular enzymes that cleave most prohormones ａnd neuropeptide precursors. Numerous other cellular proteins, some viral proteins, ａnd bacterial toxins that are transported by the constitutive secretory pathway are also targeted for maturation by PCs. PC family members share structural similarities, which include a heterogeneous ~10 kDa amino-terminal proregion, a highly conserved ~55 kDa subtilisin-like catalytic domain, ａnd carboxyl-terminal domain that is heterogeneous in length ａnd sequence. These enzymes become catalytically active following proregion cleavage within the appropriate cellular compartment. The subcellular localization of PC family members varies. Immunolocalization studies show that PC1 is found in the perinuclear region as well as the trans-Golgi network, whereas PC2 can be found in the trans-Golgi network as well as diffusely distributed in the peripheral cytoplasm.Subcellular Location : Membrane; Single-pass type II membrane protein. Basolateral cell membrane; Single-pass type II membrane protein.Tissue Specificity : Expressed in plasma cells ａnd also in a number of non-lymphoid tissues, including the distal convoluted tubule of the kidney, chondrocytes ａnd epididymis.Similarity : Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.Contains 2 SMB （somatomedin-B） domains.Subunit : Homodimer; disulfide-linked.

核苷酸内焦磷酸酶/磷酸二酯酶1抗体的质量标准：

■其它名称：	ENPP1; ENPP 1; ENPP-1; PC1; PC-1; ectonucleotide pyrophosphatase/phosphodiesterase 1; Plas
■交叉反应：	hu, rat, mo, Rb
■产品类型：	一抗
■应用领域:	/肿瘤/免疫学/信号转导/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 100kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human ENPP1 N-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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核苷酸内焦磷酸酶/磷酸二酯酶1抗体Anti-ENPP1的相关产品目录：







1mg/1ml 核苷酸内焦磷酸酶/磷酸二酯酶1抗体 Anti-ENPP1 ENPP1; ENPP 1; ENPP-1; PC1; PC-1; ectonucleotide pyrophosphatase/phosphodiesterase 1; Plas的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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