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磷酸化GADD153抗体 Anti-phospho-GADD153 (Ser30) 田源一抗磷酸化抗体
点击次数:148发布时间:2012/8/2 11:29:59
更新日期:2013/3/22 10:33:50
所 在 地:其它
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详细内容
磷酸化GADD153抗体Anti-phospho-GADD153 (Ser30)Growth arrest and DNA damage-inducible 153; C/EBP homologous protein; C/EBP Homology Prote
360TIYO.COM-上海田源公司
性能参数:
中文名称:磷酸化GADD153抗体
英文名称:Anti-phospho-GADD153 (Ser30)
别名:Growth arrest and DNA damage-inducible 153; C/EBP homologous protein; C/EBP Homology Prote
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:GADD153 (Growth arrest and DNA damage-inducible 153; DNA-damage inducible transcript 3;) is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.GADD153蛋白与细胞凋亡和死亡密切相关,在某种程度上决定了细胞周期的进程。磷酸化GADD153抗体的质量标准:
■其它名称: | Growth arrest and DNA damage-inducible 153; C/EBP homologous protein; C/EBP Homology Prote |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /免疫学/信号转导/细胞凋亡/细胞周期蛋白/转录调节因子 |
■蛋白分子: | predicted molecular weight: 31kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human GADD153 around the phosphorylation site of Ser30 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化GADD153抗体Anti-phospho-GADD153 (Ser30)的相关产品目录:
1mg/1ml 磷酸化GADD153抗体 Anti-phospho-GADD153 (Ser30) Growth arrest and DNA damage-inducible 153; C/EBP homologous protein; C/EBP Homology Prote的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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