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葡萄糖转运蛋白2抗体 Anti-GLUT2 田源一抗
点击次数:160发布时间:2012/8/2 11:33:43
更新日期:2013/3/22 10:33:23
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详细内容
葡萄糖转运蛋白2抗体Anti-GLUT2liver; Glucose Transporter 2; Glucose Transporter GLUT2; Glucose transporter type 2; Gluco
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性能参数:
中文名称:葡萄糖转运蛋白2抗体
英文名称:Anti-GLUT2
别名:liver; Glucose Transporter 2; Glucose Transporter GLUT2; Glucose transporter type 2; Gluco
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. [provided by RefSeq, Jul 2008]. Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.Subcellular Location : Membrane; Multi-pass membrane protein.Tissue Specificity : Liver, insulin-producing beta cell, small intestine and kidney.Similarity : Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.交换和转运(Trafficking and Transport) 葡萄糖载运蛋白2 GLUT-2是胰岛B细胞膜上的转运蛋白,在血糖浓度升高时,促进GLUT2对葡萄糖的转运功能,继而刺激胰岛素释放。GLUT2分子对葡萄糖亲合力极低,似乎仅在血浆葡萄糖水平相对较高时才作为转运体发挥载体功能,GLUT2在胰岛B细胞的葡萄糖转运中起着重要作用GLUT-2和GLUT-4蛋白这两个葡萄糖运载体的研究对于糖尿病的胰岛素释放障碍和胰岛素抵抗有重要意义葡萄糖转运蛋白2抗体的质量标准:
■其它名称: | liver; Glucose Transporter 2; Glucose Transporter GLUT2; Glucose transporter type 2; Gluco |
■交叉反应: | hu, mo, rat, cow, shp, pig, dog, chk |
■产品类型: | 一抗 |
■应用领域: | /细胞生物/免疫学 |
■蛋白分子: | predicted molecular weight: 54kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human GLUT2 (465-513aa) |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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葡萄糖转运蛋白2抗体Anti-GLUT2的相关产品目录:
1mg/1ml 葡萄糖转运蛋白2抗体 Anti-GLUT2 liver; Glucose Transporter 2; Glucose Transporter GLUT2; Glucose transporter type 2; Gluco的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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