乳腺癌易感基因环状结构域蛋白抗体Anti-BARD1BARD-1; Bard1; Bard 1; BARD1_HUMAN; BRCA1 associated RING domain 1; BRCA1 associated RING
360TIYO.COM-上海田源公司

性能参数：

中文名称：乳腺癌易感基因环状结构域蛋白抗体
英文名称：Anti-BARD1
别名：BARD-1; Bard1; Bard 1; BARD1_HUMAN; BRCA1 associated RING domain 1; BRCA1 associated RING
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：BRCA1 Associated RING Domain gene 1 （BARD1） interacts with the N terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo ａnd in vitro, BARD1 shares homology with the 2 most conserved regions of BRCA1: the N terminal RING motif ａnd the C terminal BRCT domain. The RING motif is a cysteine rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes ａnd dominant protooncogenes. The BARD1 protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. BARD1 may be the target of oncogenic mutations in breast or ovarian cancer. BARD1 also plays a role in mediating apoptotic stress ａnd p53 dependent.Subcellular Location : Nucleus.Similarity : Contains 4 ANK repeats. Contains 2 BRCT domains. Contains 1 RING-type zinc finger.Subunit : Homo- ａnd heterodimer. Heterodimer

乳腺癌易感基因环状结构域蛋白抗体的质量标准：

■其它名称：	BARD-1; Bard1; Bard 1; BARD1_HUMAN; BRCA1 associated RING domain 1; BRCA1 associated RING
■交叉反应：	hu, mo, rat, cow, hrs, pig, dog, chk
■产品类型：	一抗
■应用领域:	/肿瘤/细胞生物/免疫学/染色质和核信号/细胞凋亡
■蛋白分子：	predicted molecular weight: 85kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human BARD1
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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1、向我们的客户服务部反应投诉原因及订单信息。
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由于化学产品的特殊性，恕不接受以下投诉：
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乳腺癌易感基因环状结构域蛋白抗体Anti-BARD1的相关产品目录：







1mg/1ml 乳腺癌易感基因环状结构域蛋白抗体 Anti-BARD1 BARD-1; Bard1; Bard 1; BARD1_HUMAN; BRCA1 associated RING domain 1; BRCA1 associated RING 的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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