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促代谢型谷氨酸受体2抗体 田源一抗
点击次数:104发布时间:2012/8/3 17:49:12
更新日期:2013/5/3 14:36:20
所 在 地:其它
产品型号:Anti-GRM2/GLUR2
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详细内容
促代谢型谷氨酸受体2抗体Anti-GRM2/GLUR2Glutamate Receptor Metabotropic 2; Gprc1b; AMPA selective glutamate receptor 2; GLUR 2; GL
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性能参数:
中文名称:促代谢型谷氨酸受体2抗体
英文名称:Anti-GRM2/GLUR2
别名:Glutamate Receptor Metabotropic 2; Gprc1b; AMPA selective glutamate receptor 2; GLUR 2; GL
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.Subcellular Location : Cell membrane; Multi-pass membrane protein.Similarity : Belongs to the G-protein coupled receptor 3 family.Subunit : Interacts with GRASP (By similarity).谷氨酸受体-代谢能2;主要参与细胞信号转导及突触传递,在G蛋白偶联受体蛋白信号转导途径中有一定的作用,并且有负调控腺苷酸环化酶的作用,为膜性蛋白,在胞膜、胞浆中表达。促代谢型谷氨酸受体2抗体的质量标准:
■其它名称: | Glutamate Receptor Metabotropic 2; Gprc1b; AMPA selective glutamate receptor 2; GLUR 2; GL |
■交叉反应: | hu, rat, mo |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/免疫学/信号转导/细胞凋亡 |
■蛋白分子: | predicted molecular weight: 96kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human GRM2 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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促代谢型谷氨酸受体2抗体Anti-GRM2/GLUR2的相关产品目录:
1mg/1ml 促代谢型谷氨酸受体2抗体 Anti-GRM2/GLUR2 Glutamate Receptor Metabotropic 2; Gprc1b; AMPA selective glutamate receptor 2; GLUR 2; GL的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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