组蛋白去乙酰化酶3抗体Anti-HDAC3/HD3RPD3 2; HD 3; HD3; HDAC 3; Histone deacetylase 3 （HD3） （RPD3-2）; histone deacetylase 3; RP
360TIYO.COM-上海田源公司

性能参数：

中文名称：组蛋白去乙酰化酶3抗体
英文名称：Anti-HDAC3/HD3
别名：RPD3 2; HD 3; HD3; HDAC 3; Histone deacetylase 3 （HD3） （RPD3-2）; histone deacetylase 3; RP
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Histones play a critical role in transcriptional regulation, cell cycle progression, ａnd developmental events. Histone acetylation/deacetylation alters chromosome structure ａnd affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone acetylase/acuc/apha family. It has histone deacetylase activity ａnd represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function ａnd thus modulate cell growth ａnd apoptosis. This gene is regarded as a potential tumor suppressor gene.Subcellular Location : Nucleus.Tissue Specificity : Widely expressed.Similarity : Belongs to the histone deacetylase family. HD type 1 subfamily.Subunit : Interacts with HDAC7 ａnd HDAC9. Forms a heterologous complex at least with YY1. Interacts with DAXX, HDAC10 ａnd DACH1. Found in a complex with NCOR1 ａnd NCOR2. Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A ａnd GPS2. Interacts with BCOR, MJD2A/JHDM3A, NRIP1, PRDM6 ａnd SRY. Interacts with BTBD14B. Interacts with GLIS2. Interacts （via the DNA-binding domain） with NR2C1; the interaction recruits phosphorylated NR2C1 to PML bodies for sumoylation. Component of the Notch corepressor complex. Interacts with CBFA2T3 ａnd NKAP. Interacts with APEX1; the interaction is not dependent on the acetylated status of APEX1. Interacts with ａnd deacetylates MAPK14. Interacts with ZMYND15.组蛋白去乙酰化酶（HDACs）是一组在细胞染色质水平、通过诱导组蛋白去乙酰化来调控包括染色质重组、转录活化或抑制、细胞周期、细胞分化及细胞凋亡等一系列生物学效应的酶，特别是与细胞活化后的基因转录表达调控有关。

组蛋白去乙酰化酶3抗体的质量标准：

■其它名称：	RPD3 2; HD 3; HD3; HDAC 3; Histone deacetylase 3 （HD3） （RPD3-2）; histone deacetylase 3; RP
■交叉反应：	hu, mo, rat, hrs, Rb, dog, chk
■产品类型：	一抗乙酰化抗体
■应用领域:	/肿瘤/细胞生物/发育生物学/转录调节因子/表观遗传学
■蛋白分子：	predicted molecular weight: 47kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human HDAC3 C-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

组蛋白去乙酰化酶3抗体Anti-HDAC3/HD3的相关产品目录：







1mg/1ml 组蛋白去乙酰化酶3抗体 Anti-HDAC3/HD3 RPD3 2; HD 3; HD3; HDAC 3; Histone deacetylase 3 （HD3） （RPD3-2）; histone deacetylase 3; RP的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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