产品展示
G蛋白偶联受体109A抗体 田源一抗
点击次数:98发布时间:2012/8/3 17:57:24
更新日期:2013/5/3 14:34:10
所 在 地:其它
产品型号:Anti-GPR109A/HM74A
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详细内容
G蛋白偶联受体109A抗体Anti-GPR109A/HM74AG-protein coupled receptor 109A; GPR109A; HM74a; HM74b; NIACR1; Puma-g; PUMAG; Niacr1; Nia
360TIYO.COM-上海田源公司
性能参数:
中文名称:G蛋白偶联受体109A抗体
英文名称:Anti-GPR109A/HM74A
别名:G-protein coupled receptor 109A; GPR109A; HM74a; HM74b; NIACR1; Puma-g; PUMAG; Niacr1; Nia
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.G蛋白偶联受体109A抗体的质量标准:
■其它名称: | G-protein coupled receptor 109A; GPR109A; HM74a; HM74b; NIACR1; Puma-g; PUMAG; Niacr1; Nia |
■交叉反应: | hu, mo, rat, pig, Rb |
■产品类型: | 一抗 |
■应用领域: | /免疫学 |
■蛋白分子: | predicted molecular weight: 40kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human GPR109A |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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2、非质量报告提及的指标投诉
G蛋白偶联受体109A抗体Anti-GPR109A/HM74A的相关产品目录:
1mg/1ml G蛋白偶联受体109A抗体 Anti-GPR109A/HM74A G-protein coupled receptor 109A; GPR109A; HM74a; HM74b; NIACR1; Puma-g; PUMAG; Niacr1; Nia的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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