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肝细胞生长因子激活物抑制剂抗体 田源一抗
点击次数:194发布时间:2012/8/3 17:57:52
更新日期:2013/5/3 14:33:57
所 在 地:其它
产品型号:Anti-HAI-1
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详细内容
肝细胞生长因子激活物抑制剂抗体Anti-HAI-1Hepatocyte Growth Factor Activator Inhibitor 1; Spint1; Hai1; HGFA Inhibitor 1; HAI-1.
360TIYO.COM-上海田源公司
性能参数:
中文名称:肝细胞生长因子激活物抑制剂抗体
英文名称:Anti-HAI-1
别名:Hepatocyte Growth Factor Activator Inhibitor 1; Spint1; Hai1; HGFA Inhibitor 1; HAI-1.
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:HGFA Inhibitor 1 is an endogenous inhibitor of the kunitz-type serine proteinase HGF-activator (HGFA). HGF was first described as a hepatocyte-specific mitogen and survival factor, and has since been shown to exert a variety of actions on many cell types by binding to its MET receptor. HGF is activated by cleavage of the single-chain form to form a two-chain version by HGFA. HGFA Inhibitor 1 also inhibits trypsin, and MTSP-1 (Matriptase), a serine proteinase that also activates HGF. HGFB Inhibitor 1 is a splice variant of HGFA Inhibitor 1, and contains a 16 amino acid insert after the first kringle domain, relative to the HGFA Inhibitor 1 sequence.Subcellular Location : Secreted.Similarity : Contains 2 BPTI/Kunitz inhibitor domains.Contains 1 LDL-receptor class A domain.Contains 1 MANSC domain.Subunit : Interacts with HGFAC.HAI-1 是一种含两个 Kunitz 域的跨膜蛋白,可抑制由细胞膜分泌的并且以游离形式存在的 HGFA 。 HAI-1 也可以作用于其它丝氨酸蛋白酶. HAI-1 主要在胎盘、肾、胰腺、前列腺和小肠,也有报道称 HAI-1 会在肝癌中表达。肝细胞生长因子激活物抑制剂抗体的质量标准:
■其它名称: | Hepatocyte Growth Factor Activator Inhibitor 1; Spint1; Hai1; HGFA Inhibitor 1; HAI-1. |
■交叉反应: | hu, rat, mo |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/免疫学/激酶和磷酸酶/细胞膜受体 |
■蛋白分子: | predicted molecular weight: 58kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human HAI-1 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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肝细胞生长因子激活物抑制剂抗体Anti-HAI-1的相关产品目录:
1mg/1ml 肝细胞生长因子激活物抑制剂抗体 Anti-HAI-1 Hepatocyte Growth Factor Activator Inhibitor 1; Spint1; Hai1; HGFA Inhibitor 1; HAI-1.的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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