产品展示
白介素-17抗体(人) 田源一抗
点击次数:119发布时间:2012/8/4 23:56:04
更新日期:2013/5/3 14:32:06
所 在 地:其它
产品型号:Anti-IL-17 (human)
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详细内容
白介素-17抗体(人)Anti-IL-17 (human)Other Aliases: Interleukin-17; CTLA 8 ; CTLA8; Cytotoxic T lymphocyte associated antigen 8
360TIYO.COM-上海田源公司
性能参数:
中文名称:白介素-17抗体(人)
英文名称:Anti-IL-17 (human)
别名:Other Aliases: Interleukin-17; CTLA 8 ; CTLA8; Cytotoxic T lymphocyte associated antigen 8
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:IL17, also known as CTLA8, is a T cell derived hematopoietic cytokine. It was originally cloned from a T cell hybridoma produced by fusion of a mouse cytotoxic T cell clone and a rat T lymphoma. IL17 exhibits multiple biological activities on a variety of cells including: the induction of IL6, IL8 and GCSF production in fibroblasts; the enhancement of surface expression of ICAM 1 in fibroblasts; activation of NF kappaB and costimulation of T cell proliferation. IL17 is an approximately 16 kDa polypeptide of 136 amino acids. The precursor form of IL17 consists of 155 amino acids. To generate the mature IL17 (136 amino acids), the precursor cleaves a 19 amino acid signal peptide. Human IL17 shows approximately 62.5% amino acid homology to mouse IL17 and 58% amino acid homology to rat IL17.[SUBUNIT] Homodimer.白细胞介素17(IL-17A)是一种来源于活化T淋巴细胞的细胞因子,具有较广泛的生物学活性,它能够通过诱导基质细胞产生前炎性细胞因子和造血细胞因子参与机体免疫调节及部分炎症反应,因此白细胞介素IL-17A可能是某些疾病发生发展的重要因素。人IL-17A与人IL-17F的同源性为40%,人与小鼠的IL-17F同源性近80%。Interleukin-17 原称CTLA-8, 是T细胞表达的多肽,参与造血干系统的调节,已经显示IL-17促进纤维母细胞产生IL-6,IL-8和G-CSF。白介素-17抗体(人)的质量标准:
■其它名称: | Other Aliases: Interleukin-17; CTLA 8 ; CTLA8; Cytotoxic T lymphocyte associated antigen 8 |
■交叉反应: | hu |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/细胞生物/免疫学 |
■蛋白分子: | predicted molecular weight: 16kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human IL-17 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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白介素-17抗体(人)Anti-IL-17 (human)的相关产品目录:
1mg/1ml 白介素-17抗体(人) Anti-IL-17 (human) Other Aliases: Interleukin-17; CTLA 8 ; CTLA8; Cytotoxic T lymphocyte associated antigen 8的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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