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白细胞介素-12受体β1抗体 田源一抗
点击次数:142发布时间:2012/8/4 23:57:09
更新日期:2013/5/3 14:31:53
所 在 地:其它
产品型号:Anti-IL-12RB1/CD212
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详细内容
白细胞介素-12受体β1抗体Anti-IL-12RB1/CD212Interleukin-12 receptor subunit beta-1; IL12RB1; CD212; IL-12R-BETA1; IL12RB; MGC34454; "I
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性能参数:
中文名称:白细胞介素-12受体β1抗体
英文名称:Anti-IL-12RB1/CD212
别名:Interleukin-12 receptor subunit beta-1; IL12RB1; CD212; IL-12R-BETA1; IL12RB; MGC34454; "I
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq].Subcellular Location : Membrane; Single-pass type I membrane protein.Similarity : Belongs to the type I cytokine receptor family. Type 2 subfamily.Contains 5 fibronectin type-III domains.Subunit : Dimer or oligomer; disulfide-linked. Interacts with IL12RB2 to form the high affinity IL12 receptor. Heterodimer with IL23R; in presence of IL23. The heterodimer forms the IL23 receptor.白细胞介素-12受体β1抗体的质量标准:
■其它名称: | Interleukin-12 receptor subunit beta-1; IL12RB1; CD212; IL-12R-BETA1; IL12RB; MGC34454; "I |
■交叉反应: | mo, rat |
■产品类型: | 一抗 |
■应用领域: | /免疫学/细胞膜受体 |
■蛋白分子: | predicted molecular weight: 81kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from mouse IL-12RB1 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//Flow-Cyt=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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白细胞介素-12受体β1抗体Anti-IL-12RB1/CD212的相关产品目录:
1mg/1ml 白细胞介素-12受体β1抗体 Anti-IL-12RB1/CD212 Interleukin-12 receptor subunit beta-1; IL12RB1; CD212; IL-12R-BETA1; IL12RB; MGC34454; "I的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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