产品展示
白细胞介素31抗体 田源一抗
点击次数:105发布时间:2012/8/4 23:57:47
更新日期:2013/5/3 14:31:53
所 在 地:其它
产品型号:Anti-IL-31
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详细内容
白细胞介素31抗体Anti-IL-31Interleukin-31; 1700013B14RIK, IL31; interleukin-31 precursor.
360TIYO.COM-上海田源公司
性能参数:
中文名称:白细胞介素31抗体
英文名称:Anti-IL-31
别名:Interleukin-31; 1700013B14RIK, IL31; interleukin-31 precursor.
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia and skin lesions, and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.Subcellular Location : Secreted.Tissue Specificity : Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.IL-31是一种新型T细胞衍生的细胞因子,其功能受体复合物是由IL-31RA/GPL/GLM R和OSMR组成的异二聚体。它们在过敏性和非过敏性疾病中起重要作用。白细胞介素31抗体的质量标准:
■其它名称: | Interleukin-31; 1700013B14RIK, IL31; interleukin-31 precursor. |
■交叉反应: | hu |
■产品类型: | 一抗 |
■应用领域: | /免疫学 |
■蛋白分子: | predicted molecular weight: 16kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human IL-31 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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白细胞介素31抗体Anti-IL-31的相关产品目录:
1mg/1ml 白细胞介素31抗体 Anti-IL-31 Interleukin-31; 1700013B14RIK, IL31; interleukin-31 precursor.的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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