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白细胞介素-18/干扰素γ诱导因子抗体 田源一抗
点击次数:140发布时间:2012/8/4 23:58:41
更新日期:2013/6/8 10:25:00
所 在 地:其它
产品型号:Anti-IL-18/IGIF
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详细内容
白细胞介素-18/干扰素γ诱导因子抗体Anti-IL-18/IGIFinterferon gamma-inducing factor IGIF; Interferon gamma-inducing factor; IFN-gamma-inducin
360TIYO.COM-上海田源公司
性能参数:
中文名称:白细胞介素-18/干扰素γ诱导因子抗体
英文名称:Anti-IL-18/IGIF
别名:interferon gamma-inducing factor IGIF; Interferon gamma-inducing factor; IFN-gamma-inducin
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells.This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.IL18 also has other biological properties such as stimulation of Fas ligand expression, and induction of CC and CXC chemokines. IL18 increases production of competent HIV. IL18 is related to the IL1 family. One of the IL18 receptor chains is the IL1 receptor-related protein, a member of the IL 1R family. Like IL1 , IL18 is first synthesized as a leaderless precursor requiring the IL1 converting enzyme (ICE) for cleavage into an active molecule. IL18 may play a role in tissue injury in inflammatory reactions.IL-18是巨噬细胞分泌的一个重要因子,它具有多种免疫功能,能诱导产生IFNγ,无论在病毒感染早期或特异性细胞免疫应答效应阶段都会出现,因此IL-18主要参与免疫应答及炎性细胞浸润的改变。Interleukin-18 又称inteferon-gamma inducing factor(IGIF),在辅助T细胞的应答反应中起重要作用。IL-18和IL-1一起,既参与先天免疫,又是后天免疫的构成因素。白细胞介素-18/干扰素γ诱导因子抗体的质量标准:
■其它名称: | interferon gamma-inducing factor IGIF; Interferon gamma-inducing factor; IFN-gamma-inducin |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | /免疫学 |
■蛋白分子: | predicted molecular weight: 22kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human IL-18 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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白细胞介素-18/干扰素γ诱导因子抗体Anti-IL-18/IGIF的相关产品目录:
1mg/1ml 白细胞介素-18/干扰素γ诱导因子抗体 Anti-IL-18/IGIF interferon gamma-inducing factor IGIF; Interferon gamma-inducing factor; IFN-gamma-inducin的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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