白细胞介素6受体α抗体IL-6RαAnti-IL-6R αIL6R-alpha; IL-6R Alpha; gp80; IL-6Rα; Membrane glycoprotein 80; CD 126; CD126; CD126 anti
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性能参数：

中文名称：白细胞介素6受体α抗体IL-6Rα
英文名称：Anti-IL-6R α
别名：IL6R-alpha; IL-6R Alpha; gp80; IL-6Rα; Membrane glycoprotein 80; CD 126; CD126; CD126 anti
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：IL6 exerts its activity through binding to a high affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa IL6 binding receptor protein （IL6R） ａnd a 130 kDa signal transducing protein consisting of a 19 amino acid residue signal peptide （gp130）. Human IL6R is a 468 amino acid residue type I membrane protein consisting of a 19 amino acid residue signal peptide, a 339 residue extracellular region, a 28 residue transmembrane region ａnd an 82 residue cytoplasmic region. The ectodomain of IL6R is made up of an immunoglobulin like domain ａnd a cytokine receptor superfamily domain. A naturally occurring soluble form of the IL6R, which binds IL6 ａnd which mediates IL6 signaling through interaction with gp130, is identified in the urine of healthy adult humans. It has also been detected in human ａnd mouse serum as well as in the conditioned medium of various cells including human peripheral blood mononuclear cells, ａnd several T cell or granulocyte/macrophage cell lines. Increased expression of the c-fos ａnd c-myc protooncogenes have been linked to IL6 receptor activation.Subcellular Location : Isoform 1: Basolateral cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.Tissue Specificity : Isoform 2 is expressed in peripheral blood mononuclear cells ａnd weakly found in urine ａnd serum.Similarity : Belongs to the type I cytokine receptor family. Type 3subfamily. Contains 1 fibronectin type-III domain. Contains 1 Ig-like C2-type （immunoglobulin-like） domain.Subunit : Hexamer of two molecules each of IL6, IL6R ａnd IL6ST.

白细胞介素6受体α抗体IL-6Rα的质量标准：

■其它名称：	IL6R-alpha; IL-6R Alpha; gp80; IL-6Rα; Membrane glycoprotein 80; CD 126; CD126; CD126 anti
■交叉反应：	mo, rat
■产品类型：	一抗
■应用领域:	/细胞生物/免疫学/细胞膜受体/细胞表面分子
■蛋白分子：	predicted molecular weight: 50kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from mouse IL-6R alpha C-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
4、田源将联系客户并提供质量投诉处理结果。

友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

白细胞介素6受体α抗体IL-6RαAnti-IL-6R α的相关产品目录：







1mg/1ml 白细胞介素6受体α抗体IL-6Rα Anti-IL-6R α IL6R-alpha; IL-6R Alpha; gp80; IL-6Rα; Membrane glycoprotein 80; CD 126; CD126; CD126 anti的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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