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热休克因子1抗体Anti-HSF1Heat shock factor 1; Heat shock factor protein 1; Heat shock transcription factor 1; HSF 1
360TIYO.COM-上海田源公司
性能参数:
中文名称:热休克因子1抗体
英文名称:Anti-HSF1
别名:Heat shock factor 1; Heat shock factor protein 1; Heat shock transcription factor 1; HSF 1
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Two HSFs have been identified in human cells, HSF 1 and HSF 2, which bind to the same HSEs and have 38% sequence identity. These factors are activated by distinct stimuli, HSF 1 is responsive to classical stress signals such as heat, heavy metals and oxidative reagents, whereas HSF 2 is activated during hemin-mediated differentiation of human erythroleukemia cells. HSF 1 exists constitutively in the cytoplasm and the nucleus of unstressed cells as a monomer which lacks DNA binding activity. Through an unknown signal generated during stress, HSF 1 becomes activated to a nuclear localized, trimeric state which binds to DNA. The phosphorylation of HSF 1 is necessary for maximal transcription of heat shock genes.Subcellular Location : Cytoplasm. Nucleus.Similarity : Belongs to the HSF family.Subunit : Monomer.热休克因子1抗体的质量标准:
■其它名称: | Heat shock factor 1; Heat shock factor protein 1; Heat shock transcription factor 1; HSF 1 |
■交叉反应: | hu, mo, rat, Rb, cow, pig, dog |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/细胞生物/免疫学/信号转导/细胞凋亡/转录调节因子 |
■蛋白分子: | predicted molecular weight: 57kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human HSF1 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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热休克因子1抗体Anti-HSF1的相关产品目录:
1mg/1ml 热休克因子1抗体 Anti-HSF1 Heat shock factor 1; Heat shock factor protein 1; Heat shock transcription factor 1; HSF 1的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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