产品展示
白介素15受体α抗体 田源一抗
点击次数:139发布时间:2012/8/5 0:00:18
更新日期:2013/6/8 10:22:58
所 在 地:其它
产品型号:Anti-IL-15RA
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详细内容
白介素15受体α抗体Anti-IL-15RAInterleukin-15 receptor subunit alpha; IL 15R alpha; IL15RA; Interleukin 15 receptor alpha
360TIYO.COM-上海田源公司
性能参数:
中文名称:白介素15受体α抗体
英文名称:Anti-IL-15RA
别名:Interleukin-15 receptor subunit alpha; IL 15R alpha; IL15RA; Interleukin 15 receptor alpha
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:IL15RA is a cytokine receptor that specifically binds IL15 with high affinity. It shares two subunits with the receptor of IL2, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. There are nine different isoforms.Subcellular Location : Membrane. Nucleus membrane; Isoform 5, isoform 6, isoform 7 and isoform 8 are associated with endoplasmic reticulum, Golgi and cytoplasmic vesicles, but not with the nuclear membrane. Soluble interleukin-15 receptor subunit alpha: Secreted, extracellular space.Tissue Specificity : Isoform 1, isoform 3, isoform 4, isoform 5, isoform 6, isoform 7, isoform 8 and isoform 9 are widely expressed. Expressed in fetal brain with higher expression in the hippocampus and cerebellum than in cortex and thalamus. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.Similarity : Contains 1 Sushi (CCP/SCR) domain.白介素15受体α抗体的质量标准:
■其它名称: | Interleukin-15 receptor subunit alpha; IL 15R alpha; IL15RA; Interleukin 15 receptor alpha |
■交叉反应: | hu, mo, rat, dog, cow, hrs, Rb |
■产品类型: | 一抗 |
■应用领域: | /免疫学 |
■蛋白分子: | predicted molecular weight: 29kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human IL-15RA C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//Flow-Cyt=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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白介素15受体α抗体Anti-IL-15RA的相关产品目录:
1mg/1ml 白介素15受体α抗体 Anti-IL-15RA Interleukin-15 receptor subunit alpha; IL 15R alpha; IL15RA; Interleukin 15 receptor alpha的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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