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白介素16抗体 田源一抗
点击次数:163发布时间:2012/8/5 0:15:43
更新日期:2013/6/8 9:48:47
所 在 地:其它
产品型号:Anti-IL-16
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详细内容
白介素16抗体Anti-IL-16Interleukin-16; HGNC:5980; HsT19289; Interleukin 16 precursor; LCF; Lymphocyte Chemotactic
360TIYO.COM-上海田源公司
性能参数:
中文名称:白介素16抗体
英文名称:Anti-IL-16
别名:Interleukin-16; HGNC:5980; HsT19289; Interleukin 16 precursor; LCF; Lymphocyte Chemotactic
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:IL16 is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR)/CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils.Subcellular Location : Secreted (By similarity). Isoform 1: Cytoplasm. Note=Colocalizes with GRIN2C in neuronal cell bodies and neurites. Isoform 2: Cytoplasm. Nucleus (By similarity).Tissue Specificity : Isoform 1 is expressed in neurons of the cerebellum and hippocampus. Isoform 2 is expressed in thymus, spleen and lung.Similarity : Contains 4 PDZ (DHR) domains.Subunit : Homotetramer (Probable). Isoform 2 interacts with GRIN2A. Isoform 1 interacts with GRIN2D, KCNJ10, KCNJ15 and CACNA1C.Isoform 2 interacts (via PDZ 3 domain) with PPP1R12A, PPP1R12B and PPP1R12C. Isoform 1 interacts with PPP1R12B. Isoform 3 interacts with GABPB1. Isoform 2 interacts (via PDZ 3 domain) with HDAC3 (By similarity).白介素16抗体的质量标准:
■其它名称: | Interleukin-16; HGNC:5980; HsT19289; Interleukin 16 precursor; LCF; Lymphocyte Chemotactic |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | /免疫学 |
■蛋白分子: | predicted molecular weight: 13/76/147kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human IL-16 N-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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白介素16抗体Anti-IL-16的相关产品目录:
1mg/1ml 白介素16抗体 Anti-IL-16 Interleukin-16; HGNC:5980; HsT19289; Interleukin 16 precursor; LCF; Lymphocyte Chemotactic的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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